I just had a full upper endoscopy by a top GI doctor in Chicago.
NO acid damage (or any other kind of damage) was found. No Barrett's, strictures, etc. No hiatal hernia either.
He did biopsies to check for microscopic damage: none was found.
My TNE I had a month ago showed nothing.
So here is the deal: if you are suffering from symptoms that look like LPR (hoarse voice, globus, throat irritation, etc.) it may not be LPR at all. It may be a low-level infection of the maxillary sinus cavities, asthma, severe allergies, or some other issue. I've been getting nose bleeds in the morning when I wake up, so there is something up with my sinuses (again).
When big doses of PPIs and dietary restrictions were doing absolutely nothing to help my symptoms, I began to suspect that LPR was not the problem.
I did a lot of research on LPR (reading studies, clinical manuals, doctor's opinions, etc.) and realized that this condition is
a) WAY over-diagnosed
b) Frequently mis-diagnosed
c) Does not respond well to treatment (because it is often misdiagnosed: PPIs won't help you if your problem isn't LPR)
d) Does not respond well to surgery over the long-term
Dr. Jamie Koufman is the big cheerleader for LPR, but her theories are controversial and untested.
I am not a doctor, but my recommendation is this: if you have a clear upper endoscopy, no hiatal hernia, etc., you don't have an acid problem. Your issues are going top-down, not bottom up. Don't spend huge sums of money of reflux medications, special diets, silly books, and worry yourself sick. Your anxiety will go through the roof, causing more esophogeal spasms (happened to me: more I worried about it, the worse it got). Begin to focus on the real problem: get a CT scan of the sinuses if necessary (or an endoscopy), start irrigating, talk to an ENT.