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Veteran Member

Date Joined Jun 2005
Total Posts : 527
   Posted 3/28/2012 10:37 PM (GMT -6)   
I have been diagnosed w Esophageal spasm..("Corkscrew Esophagus" ...Dx.from a Barium swallow)-    And Gerd--!  Bad combo--
The Esopgageal spasm...a times is very painful--My Gastro Dr---gave me Hyoscomine..under the tongue--!     Just OK--
What DOES help---my wife crushes uo some peppermint vandy,,,(the kind with REAL "peppermint oil" it)--then I mix it w some water..& it makes a paste---I eat a little at a time--
Peppermint oil---has an "Anti Spasmodic"..quality...& really DOES help w the spasm--try it--sometime---!   Only thing is...peppermint oil causes acid...!  I double edged sword!
Anyway--for my Gerd.... years ago---I was on "Protonix"...40 mg..for a few yrs----then Zantac,,,NOW..I;m using Zegerid...OTC....(I wanna take the lowest effctive dose...AND I can take...them....2 times/day...AM...7 PM)---Also----It contains Sodium  Bicarbonate...which helps--
I'm thinking about getting an Endoscopy...(I had a colonoscopy past June...everything was normal-!    Kinda upset w myself for not ASKING,,,(While I was UNDER sedation)---for an endoscope!   Hoping I do not have Barrets---some nites the..."acid reflux".;..seems more ..."Resistant" the PPI---!
My question,,to ALL of you out there---WHICH of the "Proton Pump Inhibitors"., you find most effective--?!

Veteran Member

Date Joined Jan 2011
Total Posts : 513
   Posted 3/29/2012 7:19 AM (GMT -6)   
Hi , ive have tried every h2 blocker and ppi in my history with gerd and the most effective medication was Nexium or esomeprazole! saying that i also had some bad side effects on it.Everyone seems to react differently to the various meds aswell and i think its a matter of try it and see what works best for you. Nexium comes in 20mg or 40mgs. Barry.

Regular Member

Date Joined Nov 2011
Total Posts : 148
   Posted 3/29/2012 12:36 PM (GMT -6)   
Most effective PPI is Nexium.

Regular Member

Date Joined Jan 2012
Total Posts : 36
   Posted 3/29/2012 12:41 PM (GMT -6)   
I have been on at least a half dozen different PPI's over maybe 15- 20 years. Often after many years they would just stop being effective. Nexium, after I was put on it twice a day, was very effective, except my insurance company, in their infinite wisdom, decided not to cover it any more. Then I bounced between several different ones, which were not as effective until I tried Zegerid which was fine.

I had my surgery in February and was given nothing for the first two weeks until my surgeon felt that I was having a rebound effect and put me on a small dose of protonix, which I am slowly weaning off .

Regular Member

Date Joined May 2011
Total Posts : 127
   Posted 3/29/2012 3:42 PM (GMT -6)   
Hi Barry,

I have tried omeprazole (Prilosec) 20 mg and found that it did a 'decent' job at controlling my GERD but not the LPR so much. I now take Prevacid (lansoprazole) 30 mg and I can eat many things that I could not while on Prilosec. That said, I do follow a strict, GERD approved diet MOST of the time. I am however able to consume alcohol on the Prevacid so that seems pretty impressive to me.
That's my two cents worth...Good luck!

take care,

Regular Member

Date Joined Jan 2012
Total Posts : 87
   Posted 3/29/2012 5:53 PM (GMT -6)   
I've tried prilosec (omeprazole), prevacid (lansoprazole), and nexium (esomeprazole). I've had the most success with Nexium, thus far. I figured it would be just the same as prilosec, but it's definitely more effective for me.

Good luck.

Regular Member

Date Joined Jan 2012
Total Posts : 36
   Posted 3/29/2012 7:20 PM (GMT -6)   
I have found that different pills work better for different folks. While I was pretty happy on nexium, but miserable when forced to switch to aciphex, for my cousin the opposite was true.

I have been on all that you mentioned plus many more. The fact that they were not working so well, combined with a careful diet and even purchasing a bed , like a hospital bed that can be raised up before I go to sleep was why I finally chose to have the surgery.

Regular Member

Date Joined Nov 2011
Total Posts : 148
   Posted 3/29/2012 9:38 PM (GMT -6)   
Just a caution, before you find the best PPI and hooked to it, please try natural alternatives first.

New Member

Date Joined Apr 2012
Total Posts : 1
   Posted 4/4/2012 7:39 PM (GMT -6)   
hey i noticed ive been going through the exact same feelings as you and i also am terrified i have multiple sclerosis im 15 years old malo and i started with the myoclonus and then it went away but started cramping and wierd feeling like bad blood circulation in my legs and now its back again....i also have severe anxiety issues but im still getting a mri peace

Regular Member

Date Joined Feb 2012
Total Posts : 69
   Posted 4/5/2012 12:06 AM (GMT -6)   
I've tried just about everything on the market and Prevacid definitely worked better than anything else for me. Sometimes I'd miss it for a few days and have to take Prilosec, and there would be a clear difference, even at max dose. I started Prevacid because I read a medical journal article (New England Journal I think) that said it was slightly better than others. However, in general experience, different PPIs work better for people. They are all very similar and do basically the same thing, but the drug companies make more money by coming out with a new one. Be your own guinea pig and find what works for you.
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