Can't sleep through the night

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KitKat880
Regular Member


Date Joined Apr 2012
Total Posts : 132
   Posted 5/4/2012 1:27 AM (GMT -6)   
For the past week or so, I have not been able to sleep through the night. I'll go to bed around 10 pm and wake up at 2, 3, or if I'm lucky, 4 am. I don't understand what's going on here. Could this be a side effect of the Dexilant? Maybe the Lexapro? I've been dealing with the symptoms of acid reflux for months now, but this one is extremely frustrating because sleep is my only escape, and now even that has been taken from me!

I don't experience heartburn, and I thought that this symptom was the one that typically made it hard for people with GERD to get a full night's sleep...

KitKat880
Regular Member


Date Joined Apr 2012
Total Posts : 132
   Posted 5/4/2012 1:29 AM (GMT -6)   
I should add that I sleep on an incline (6") and do not eat after 6 pm.

Baza
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Date Joined Jan 2011
Total Posts : 513
   Posted 5/4/2012 3:08 AM (GMT -6)   
Hi KitKat880, i had the same problem with sleep patterns disrupted when on certain ppi,s and one in particular was Lansoprazole,i kept waking through the night no matter how tired i was.I think Dexilant has lansoprazole in its ingredients so maybe its a side effect for you aswell.Maybe you could try a different ppi like nexium to see if it makes a difference. Barry

KitKat880
Regular Member


Date Joined Apr 2012
Total Posts : 132
   Posted 5/4/2012 6:23 AM (GMT -6)   
Thanks, Barry. I was on Nexium for a few weeks, but my GI doc switched me to Dexilant because he thought the Nexium wasn't providing round the clock protection. So I doubt I'll be going back to it.
 
I was given the Lexapro for the anxiety that this illness is creating. I also have abnormal esophageal motility, which SSRIs can supposedly help with. I've been taking the Lexpro at night, so maybe I'll switch to taking it in the morning to see if that makes a difference. If it doesn't, I'll stop taking it so I can at least figure out which drug is causing the issue.

Baza
Veteran Member


Date Joined Jan 2011
Total Posts : 513
   Posted 5/4/2012 7:13 AM (GMT -6)   
Sorry your having so much trouble,i know its a nightmare with all the drugs and their side effects,its gonna be a trial and error thing. Find it strange the nexium wasnt providing full protection for you as its highly regarded as one of the top ppi,s but im no expert.I tried all ppi,s in my journey with reflux and they all have their own side effects,i found nexium provided the most protection.Hope you get sorted! Barry

speden
Regular Member


Date Joined Oct 2009
Total Posts : 175
   Posted 5/4/2012 7:59 AM (GMT -6)   
Hi KitKat,

Sleeping from 10 to 3 or 4 is a pretty good run of sleep. I don't know how old you are, but it's pretty normal to wake up at least once during the night, especially as you get older. As long as you can get back to sleep I wouldn't worry about it too much. I doubt it is a direct side effect of the PPI's, which I have found tend to improve sleep quality by reducing reflux pain.

The one exception to that which I've seen is PPI's sometimes cause extra dryness in the mouth. I often wake up in the wee hours with a dry mouth and find that having a cup of water next to my bed is helpful to take a couple sips and go back to sleep.

Also 6" elevation isn't enough if you have bad reflux. I'm elevated about 12" myself even though that causes some annoying sliding down the bed. But you have to pick your poison, and for me minimizing the reflux is number 1. Even if you don't feel heartburn, you may be waking up from reflux pain that's happening at a subconscious level. You esophagus feels that it's under the acid attack, and your body wakes up in self defense even though you don't feel pain.

6pm is kind of early to be having your last food. You may be waking up because you are getting hungry at 2am. I'd suggest adding a quickly digesting snack at 8pm or so to help you sleep longer. I find some yogurt or canned fruit is good for that.

I'd more likely suspect the anxiety meds of disrupting your sleep than the PPI's. I'd try to get off of those if you can and use natural methods to reduce anxiety.

KitKat880
Regular Member


Date Joined Apr 2012
Total Posts : 132
   Posted 5/4/2012 8:23 AM (GMT -6)   
speden,

Thanks for your reply. I'm 25. Before all of these health issues started a few months ago, I had absolutely no problems sleeping through the night. I'm also the type of person that can't run on much less than 8 hours of sleep, so waking up at 3 am is not so great. When I wake up it can take 1-2 hours to go back to sleep, and before I know it the alarm clock is ringing.

I have mild to moderate reflux, which has caused grade one esophagitis. I cringe at the idea of raising the bed any higher, but if it helps me sleep, I'll learn to live with it.

I've been eating dinner very early to try to avoid reflux during the night, but I have noticed that my stomach cramps up as it gets close to bedtime. I don't have much of an appetite and don't experience hunger pains anymore, but maybe this is my stomach's way of telling me it needs food. I will try eating something light a little closer to bedtime (but not too close!).

I agree with you about the anxiety meds. I had no trouble sleeping when I was on omeprazole and Nexium, so I guess it could be the Dexilant that specifically causes an issue for me, but I also wasn't taking the Lexapro while on the other PPIs. I took Lexapro years ago for situational depression, though in the morning rather than at night, and I never had any problems sleeping. However, I have read that Lexapro is more likely to cause insomnia in people taking it for anxiety (that's me) than for depression. I think it's odd that a drugs side effects can vary based upon the reason for taking it.

Someone on an anxiety forum suggested I ask my doctor for trazadone (another anti-depressant) to help me sleep, but I really don't want to be on another med just so I can sleep! Also, it seems ridiculous to be on two anti-depressants at once.

WJF
Regular Member


Date Joined Sep 2011
Total Posts : 273
   Posted 5/4/2012 9:05 AM (GMT -6)   
Lexapro taken at bedtime can actually help you sleep. When it is taken at morning, it can make you drowsy in the day. Sleeplessness is actually a side effect of lexapro during the starting dose, but it usually goes away.

So in your case, I think it is likely due to the anxiety (you keep thinking about your illness so it makes your subconscious very anxious even during your sleep) or dexilant or acid reflux breakthrough while you sleep.

I experienced your scenario while I was on Rabeprazole (Pariet) last year. I also had panic attack when I waked. The doctor vehemently denied that his prescription has caused the issue and asked me to stop the medication and seek help somewhere else. I stopped the medication like he instructed and only relied on Graviscon and Lexapro, strangely the GERD subsided (quite paradoxically) but anxiety and panic attack persist. I was then put on Lexapro AND valdoxan by another doctor, and that eventually resolved my insomnia. After that I had a good recovery.

KitKat880
Regular Member


Date Joined Apr 2012
Total Posts : 132
   Posted 5/4/2012 2:36 PM (GMT -6)   
WJF- Good to know that the sleeplessness eventually goes away. I do not want to stop taking the Lexapro, especially if it will help with the lump in throat feeling that is supposedly being caused by a motility issue or esopahgeal spasms.
 
I feel like I'm in a holding pattern. The reflux causes anxiety by itself, so I take Lexapro, but I have to take a PPI for the reflux, and PPIs can cause anxiety as a side effect. I don't think this will ever end! If there is a light at the end of the tunnel, the bulb must be burned out.

WJF
Regular Member


Date Joined Sep 2011
Total Posts : 273
   Posted 5/4/2012 10:24 PM (GMT -6)   
it's a self-perpetuating vicious cycle. GERD causes anxiety, anxiety aggravates GERD. The only way to break it is to endure the pain mindfully when you feel it without stirring up negative emotion and thoughts, and seek help promptly where-ever you could.
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