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LJSZ
New Member


Date Joined May 2012
Total Posts : 12
   Posted 5/24/2012 10:03 AM (GMT -6)   
New to this board.  So grateful to have found such a source of information.
I have had GERD for 3 months. During that time I have had my Gallbladder removed.  I have tried many PPIs without success including double doses of Dexilant with no help for the severe chest pain.  My primary care Physician prescribed Reglan/Metoclopramide.  This empties my stomach quickly and has helped to dull the chest pain. Does anyone know how effective this drug is over the longer term?
TIA

WJF
Regular Member


Date Joined Sep 2011
Total Posts : 273
   Posted 5/24/2012 6:04 PM (GMT -6)   
It is a very effective drug for improving stomach function to help GERD. But this drug is not meant to be taken for more than 12 weeks or higher than 40mg per day according to FDA. It can cause severe side effect which is irreversible on long term use. There are similar class of drugs: Motilium / domperidone (safer but not available in US), Propulsid / cisapride, another very effective drug that can cause dangerous side-effect and has since been pulled of shelf.

If in doubt, ask your physician about the drug, and how long he intends to put you on it.

Another note to made, is that if you have refractory symptoms despite high dose PPI, i think your physician need to think deeper to identify the cause of your acid reflux. PPI ain't no magic bullet.

couchtater
Elite Member


Date Joined Jul 2009
Total Posts : 14475
   Posted 5/24/2012 6:06 PM (GMT -6)   
I'd avoid long term use of it. I was on it for eight months and developed the shakes from it.
Just be careful with it. If you start having shakes or trembles from it stop it immediately.
Joy

LJSZ
New Member


Date Joined May 2012
Total Posts : 12
   Posted 5/24/2012 6:13 PM (GMT -6)   
Thanks Joy and WJF.
 
My new Gastro Doc has done a Manometry and Barium Swallow test but nothing showed.  I do not know what else can be done. I am starting to lose hope of ever healing and the chest pain is worse.
 
Thanks for your help and support.  Anyone else know what could be causing my acid reflux?

couchtater
Elite Member


Date Joined Jul 2009
Total Posts : 14475
   Posted 5/24/2012 8:22 PM (GMT -6)   
Have you had a stomach emptying test?
Joy

LJSZ
New Member


Date Joined May 2012
Total Posts : 12
   Posted 5/24/2012 8:43 PM (GMT -6)   
NO. It is taking so long to get these tests done I am thinking of going to the Mayo Clinic. They say they can conduct all the tests and get a diagnosis in days. I am feeling desparate.

dencha
Forum Moderator


Date Joined Feb 2009
Total Posts : 7188
   Posted 5/24/2012 10:42 PM (GMT -6)   
Hi LJSZ,
I took Reglan for several years with no untoward side effects.  I may be unusual in this, but I didn't then, and don't now, experience any of the very scary side effects that are listed as possible.
 
My PCP was quite confident that it could help my GERD, and I believe I took it for 2 to 3 years.  I never really noticed all that much difference, so quit taking it on my own.  I went back on it briefly about 6 years ago when I was hospitalized for asthma caused by a gastritis/GERD flare up. 
 
I took it for a while, but when I noticed that my thumbs were twitching a bit, I reported this and my PCP said to get off it.   My GI docs weren't fans because of the side effect risks, but as I said, I've never had any permanent damage done after taking it for several years. I am afraid I have no memory of the dosage.
 
I wouldn't hesitate to take it again for a while if it were deemed necessary.  Still, I'd be on the lookout for any twitching, etc. and report it immediately.  You can discuss all this with your doctor if you have any concerns.
 
I believe it can be really helpful for someone whose GERD is exacerbated by a slowly emptying stomach.  I just am not sure if that was my situation.  I did have a stomach emptying test while in the hospital 6 years ago, and it was deemed normal.  Strangely, though, they did the test while I was on Reglan.  Go figure.
 
Good luck with your problems.  Hopefully you'll get fixed up and feeling better very soon!  Glad you've joined the forum.
Denise
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