I'm so sorry to hear of your ordeal. I understand completely. Although my initial symptoms differ, I had very similar side effects to the medication, Dexilant. It was horrible. I felt just like you on the nexium. I was sicker taking the PPI than I was before I even had the endoscopy. My doc kept telling me to stay on the medicine. I knew in my gut (LOL) that it was making me sicker. And I chose to stop it after 3 weeks. I understand there is a 4 - 8 week withdrawal from PPI's where they can continue to make you ill. You do need to speak with your doctor about other options. I went to a new GI doc and he explained to me that there is a small group of individuals that PPI's have a negative affect upon, whereas they will increase the stomach acid as oppose to decreasing it. Apparently, this was my problem. It has now been two weeks since I'm off the Dexilant and all PPI's. I am finally beginning to feel like my self again - no more brain fog, crawling skin, volatile belly noises and movements, horrible stomach pain, and unending tears. You are not crazy. Sometimes docs need to play around with different types of meds. My new GI took me off all PPI's for now. I had a scope in October which showed inflammation where the stomach meets the esophagus. I had not feelings or symptoms of reflux until I started the ppi's. New GI has prescribed an anti-spasmodic, and zantac 150 2 x day. I have been on low acid Gerd Diet (check out Dr. Jamie Koufman's book), which is extremely difficult to do, but after 3 weeks, I am now starting to introduce some foods back in to see if I have any issues. Check with your doc to see if she/he can prescribe some Carafate Solution for you. This is wonderful stuff that will coat the inflamed tissues for a few hours. It won't heal the problem, but it will protect the inflamed area allowing it to heal faster. You may also want to check with your doc about Aloe Vera Juice (I like the George's brand, no taste, it's like drinking water) Start with a low amount though since too much Aloe can cause diarhhea in some people. I hope you start to feel better. I never knew how horrible this reflux stuff could make an individual feel. It has consumed my life for now, but I am looking forward to better days with a good diet, some natural remedies, Reiki and Yoga. It really, really is important to try to reduce your anxiety and stress levels. My docs have told me that they feel this is what caused my silent Gerd. Good Luck and I wish you well.