Stem cells for LES augmentation

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gerd_hater
Regular Member


Date Joined Oct 2012
Total Posts : 322
   Posted 12/17/2012 9:12 PM (GMT -6)   
LINX is approved, EndoStim is in trials. What next? I think some stem cell based approaches show promise.
I certainly hope that we only have to worry about imperfect solutions for just a decade more.

Summarizing what I've found so far on stem cells, googling around.

Endoscopic injection of skeletal muscle-derived cells augments gut smooth muscle sphincter function
http://www.ncbi.nlm.nih.gov/pubmed/19647239


A patent www.google.com/patents/US20070128174 on muscle derived cell injections

Urinary incontinence(similar concept) www.post-gazette.com/stories/news/health/stem-cell-injection-successfully-treats-urinary-incontinence-63736/ and original (I think 2007) trials www.icsoffice.org/Abstracts/Publish/106/000093.pdf

Autologous Cell Therapy for Treatment of Fecal Incontinence clinicaltrials.gov/ct2/show/NCT01600755

Stem cells for male incontinence post prostate cancer surgery
www.stemcellrevolution.com/currently-studying/urology/male-incontinence/

theacidrefluxman
Veteran Member


Date Joined Oct 2009
Total Posts : 739
   Posted 12/18/2012 10:29 PM (GMT -6)   
Yeah it is really interesting and promising. Makes me wish science was paramount over superstition these days but unfortunately we are not there yet. So this holy grail of medicine is not being explored as it should be.

gerd_hater
Regular Member


Date Joined Oct 2012
Total Posts : 322
   Posted 12/18/2012 11:14 PM (GMT -6)   
It is a shame that funding stopped in 2001 in the Bush era.

But seems like Pres. Obama reopened it in 2009 and I've heard that some good research labs are getting good funding now and there is a strong push towards establishing protocols for promising treatments.
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