Hi S Kendrick,
I understand what you are going through.
Obviously, the MD/MD's in charge of your sister will be addressing her acute state and find out what is wrong.
Perhaps she has an infection?
I'm confident that they will get to the actual root cause and address it very soon.
In the meantime, why don't you post your questions on the NF, so some of our moderators like Bill and Denise can help answer them? They have helped me when I was evaluating the NF for myself and are great resources.
There are also many others who can lend a helping hand. Hang in there.