Just some food for thought...... When you have a 24hr ph test done it show's xx number of reflux events (on meds). Now, ppis only lower acid in the stomach as they don't stop reflux events. So if you had a 24hr ph done (off meds) wouldn't the results be the same? Point being, if you're in the acceptable range (reflux events) on meds, what would be the point of taking meds as your reflux events would be acceptable range off meds.
It seems ppl have more non-acid reflux events on meds. This seems to support the idea that pepsin/bile are more concentrated when taking ppi's.