Can omeprazole make symptons worse?

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cairnlover
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   Posted 5/30/2013 11:18 AM (GMT -6)   
I have been on 20 omeprazole for over six months due to heartburn, reflux, discomfort, breathlessness etc. Saw consulant and had endoscopy two weeks ago when they confirmed yet again had medium hiatus hernia and copious reflux. Not heard back from Consultant as yet (ths is NHS!) but repeat prescription had a note to say to take two tablets a day at different times. So have started doing that this week but have felt much worse with more discomfort, horrid taste in mouth, feeling nausea and more breathless.
Is it the extra tablet or is it just that having flare up?


Have had diagnosis of gord, hiatus hernia, etc for over sixteen years.

DOGGBONES
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   Posted 5/30/2013 11:36 AM (GMT -6)   
When I was taking ppi's, the more I took the worse I felt. Sometimes more isn't better.....IMO.

TheSiXness
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   Posted 5/30/2013 11:45 AM (GMT -6)   
I often feel worse on PPI's too... The nausea and breathlessness is awful. I don't know if it's a flare up or just a feeling either...
-TheSixness-

Fighting daily pain from gastroparesis, gerd and lpr!
Had the TIF done 2/2012 and still am symptomatic.

drtinsac
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   Posted 5/30/2013 12:49 PM (GMT -6)   
Can you describe the taste? Is it bitter/sour, or acidic? Is it constant, or intermittent?
 
Do you have the taste even off PPI? Does adding a PPI change the characteristics of the taste?
 
The reason I'm asking all this is I have a taste too, nearly constant, and I do not believe reflux has much to do with it.

DOGGBONES
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   Posted 5/30/2013 12:56 PM (GMT -6)   
For me.....on ppi's I had water brash constantly, off ppi's I have sour taste most but not all the time. If it isn't reflux, what do you think it's from?

drtinsac
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   Posted 5/30/2013 2:03 PM (GMT -6)   
Something neurological. Since many of us here have symptoms refractory to PPIs, I think nerve issues play a part. Burning mouth syndrome for example is thought to be a neurological condition, and many BMS patients have a sour taste.

If it were actual reflux, at least in my case, I think I would be in much worse shape because it would mean my mouth (and everything between it and my stomach) would be almost constantly exposed to acid, pepsin, bile etc.

Before I had my fundo, I was convinced it was reflux. I sure wish one of my doctors had said "Wait, a CONSTANT sour taste??" and then saw that it didn't make sense with my relatively mild (yet irritating) symptoms.. it could not be actual reflux that I was tasting.

It's possible the body produces the sour substance in order to induce swallowing (by ridding the mouth of the sour taste, we are also moving saliva down which pushes any sensed reflux down).. in which case it could be connected to reflux, but not the actual taste of reflux.

cairnlover
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Total Posts : 27
   Posted 5/30/2013 2:10 PM (GMT -6)   
Mine is usually a sour taste but also I can taste the food I have eaten hours before! So on the occasion I have enjoyed a meal at time of eating it, a few hours later I no longer feel that I wish to still continue to enjoy that meal! And even worse on occasion a previous meal will flavour the next meal!

cairnlover
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   Posted 5/31/2013 9:02 AM (GMT -6)   
Oh, got call from secretary this afternoon to say consultant will be lookng at gastroscopy report etc over weekend and will let me know what could happen next after that! Had the scope just over two weeks ago.....
Hopefully he will see me again and have some advice, suggestions..... But have feelng he may just tell me to see GP.

Looeez
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   Posted 6/1/2013 5:52 AM (GMT -6)   
Have had GERD for 3 years with the biggest contributing lifestyle factor being stress. Last year my GP put me on omaprazole (seemingly forever) so from my POV it was never intended to fix my GERD. I tried them for one month but they made me feel so unwell that I stopped (similar symptoms to cairnlover). Have had some success with TCM in conjunction with dietary modifications for the past 4 months although I miss many favourite trigger foods (not their symptoms though). On the upside I am less reliant on antacids (may take only 1 per week instead of several per day) and my post meal coughing has diminished but hasn't disappeared entirely. I use this as a guide for trigger foods: http://www.aurorahealthcare.org/FYWB_pdfs/x14385.pdf

Cairnlover I hope that you get the help and advice that you're looking for. It may also be worth seeing a Dietitian for dietary advice. They won't help with the hiatus hernia but will give you helpful advice if food or alcohol are triggering your symptoms.

cairnlover
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Date Joined May 2013
Total Posts : 27
   Posted 6/1/2013 10:31 AM (GMT -6)   
Well, it is certainly not alcohol that is a trigger as do not drink any!
And cannot work out which food triggers he problems as sometimes one meal will do it and then the next time I have that there is no problem!

TheSiXness
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   Posted 6/1/2013 12:18 PM (GMT -6)   
I know I'm worse on PPi's. They make my nausea worse and it seems like they make my heartburn/ burping worse. This is something which I have been told shouldn't be happening by my UW-health doctors.

I'm on 80mg of Ommiepazolie a day. I have been diagnosed with mild gastroparesis and biliary reflux by one doctor though, so I'm thinking that those to issues maybe to blame for my worsening symptoms on PPi's.
-TheSixness-

Looeez
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   Posted 6/1/2013 3:58 PM (GMT -6)   
Cairnlover so with alcohol is was easy to work out the trigger BUT I know that it is hard with a meal to tell which was the trigger ingredient and your varied experiences with certain meals can be due to different factors. These days unless I have cooked the meal myself I can never be sure whether it is just a smidgen of butter or oil that someone has added which triggers my GERD or a pinch of seasoning, but I react immediately.
Since reading that list of food from the Aurora dietitians/dieticians website I now know from looking at the ingredient list which cuisines to avoid altogether - Mexican, Indian, Italian, Spanish and anything fatty, fried, sour or spicy in any other cuisines. Feels very limiting (especially socially) so it would be almost impossible to travel at the moment as I tend to only be able to eat what I have made at home.
On the upside since removing the trigger foods I don't wake up with a sore throat every day anymore, nor cough persistently, nor belch after every single meal but I would dearly love to eat less restrictively and miss having variety in my diet and the occasional beer which is a nono of course. I think beer, butter and cheese are the most missed and I know that they are not good for me so overall this whole situation had forced me to eat healthier foods and smaller portion sizes. I wish you all the best with getting your symptoms under control.

cairnlover
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Date Joined May 2013
Total Posts : 27
   Posted 6/1/2013 4:06 PM (GMT -6)   
Well, I do not eat spicy foods, chinese, etc. i eat a lot of chicken, fish, pork etc. i do not fry foods but either bake or microwave.
I o not eat wheat. Very rarely have cheese now. Boring really!:)

But than or he comments and supprt!

Looeez
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Date Joined Jun 2013
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   Posted 6/1/2013 4:17 PM (GMT -6)   
Yes you have certainly cut out the obvious trigger foods. A dietitian might identify more in your diet or other key causative factors. Personally I find that stress/anxiety will exacerbate my symptoms even when I haven't eaten trigger foods so I know I need to work on that although its not so simple.

Andy1986
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Date Joined Dec 2012
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   Posted 6/2/2013 3:46 PM (GMT -6)   
Cairnlover, i have found that with a hiatus hernia, trigger foods are less important than the quantity and timing of food. Your problem is physical rather than a reaction to certain foods.

You should definitely try and find any triggers you have, but be aware that even none trigger foods can give reflux episodes
GERD, Anxiety, Depression, Rolling Hiatus Hernia, Esophageal Hypersensitivity

DOGGBONES
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Date Joined Apr 2012
Total Posts : 707
   Posted 6/3/2013 5:19 AM (GMT -6)   
I have a herina, I'm not sure if it's the cause of my reflux but some days are mild and others are bad wothout changing anything.

Ricardo
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Date Joined Jul 2013
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   Posted 7/27/2013 6:25 PM (GMT -6)   
I recently had similar symptoms, originally my illness was a quiet reflux that impacted me on the throat (mostly at nights), I went to the GI and was diagnosed with non erosive reflux, First I was on 40mg Omeprazole and after 30 days I started to develop digestion issues to the point that everytime that I gave 2 bites to the meal I started feeling indigested and with a lot of belching, later I was afraid to eat because I felt that I couldn't swallow when all the belching was present, I lost 20 pounds and even that I was overweight I didn't have intention to get slim, also my reflux was not quiet anymore for the next hour or 2 after my raquitique meals I normally suffered violent reflux events and some nausea, after having a barium test that went fine my GI changed to pantoprazole 20mg (morning) + 20mg (night), to be honest, this change was positive, the eating time got better but the burping normally used to start 5 or 10 minutes after start eating so even that it was a relieve the fact that I could eat but the digestion and reflux issues were still there (altough less than with 40 mg omeprazole).

So after the medication change and the positive effects, I was dubious about my illness, I was feeling worst than when I started and with different symptoms so the only suspect were the PPIs that I was have been taking for 3 months, so after doing some research what I did 3 days ago is that I reduced my dose to only one 20mg pill in the morning and I feel much better now, the burping is almost gone and the reflux events are not that frequent.

Why I reduced my dose? well there is a condition called Achlorhydria that basically means "not enough acid in the stomach" and Achlorhydria can be triggered by PPIs of course, and even that it's still too early to sing my praises, I think that my recent problems are related and makes sense, the stomach needs acid, if there's no acid you will have bad digestion and bad digestion causes cramps, regurgitation and allergies to food, probably that's why my reflux got noisy and violent, my stomach couldn't handled it.

So Why I didn't go cold turkey with PPIs, because there is a high probability of acid production rebound and also my plan is to get a PH Test soon, the test recommendation is to wean off the PPIs for 7 days before taking the test but I am not in hurry I prefer to normalize my acid production and have the test done, I have a small sliding hiatal hernia so my reflux is confirmed no question, what doctors don't do is to find the root cause of the reflux, not all the reflux are acid and not all the acid reflux are triggered by excess of acid production in the stomach, so before accepting the PPIs we may ask if our refluxes are caused by excessive acid production or by low acid production (both conditions create similar symptoms) or to find the right cause, if you have low acid production at first you may had bad digestion so PPIs will make your condition worse. Hiatal Hernias are mechanical faciliatators for reflux but it's not normal that your stomach is spelling acids or bile towards your esophagus unless you are laid off on your bed and by simple gravity you get the heartburn.

Post Edited (Ricardo) : 7/27/2013 8:53:55 PM (GMT-6)


lobstahguy
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Date Joined Jul 2013
Total Posts : 332
   Posted 7/27/2013 7:08 PM (GMT -6)   
twice a day protonix made my throat 10 times worse and my overall health.

dencha
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Date Joined Feb 2009
Total Posts : 7181
   Posted 7/27/2013 7:12 PM (GMT -6)   
And yet, I never had a moment's problem with PPIs...It's a amazing how different everyone is.  I know others who get all kinds of side effects from medications.  I'm just not one of those, thankfully.  I've take PPIs for 20 years with no side effects.
Wish you all the best...hope things improve!
Take care,
Denise
GERD/Heartburn Moderator
Nissen Fundoplication 2/09
Allergy/Asthma

"Whatever you fight, you strengthen, and what you resist, persists.”

“Worry pretends to be necessary but serves no useful purpose”

“Accept - then act. Whatever the present moment contains, accept it as if you had chosen it. Always work with it, not against it.”
Eckhart Tolle

Ricardo
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Date Joined Jul 2013
Total Posts : 2
   Posted 7/27/2013 8:17 PM (GMT -6)   
Makes Sense Denise, probably you really had excesive acid production and PPIs are perfect for that, in my case before I ran to the Doctor I never felt heartburn, I knew it was reflux because it was mostly at night after going to bed and the choking sensation was sometimes terrible, I could feel something going slowly into my throat after 15 mins of going to bed, but my guess is that if it didn't burn my chest was probably because it was not acidic in nature and I never needed to take the PPIs at all or at least I didn't need a high dose. But I don't want to make any assumptions until I get properly tested, for now I started reducing the pantoprazole dose and my plan is to stop it completely in 2 weeks so I can do my PH test in a month.

Post Edited (Ricardo) : 7/27/2013 8:29:58 PM (GMT-6)


ericapeace2000
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Date Joined Mar 2012
Total Posts : 1110
   Posted 8/2/2013 12:25 PM (GMT -6)   
I think the PPI drugs helped me in the begining but I think over time they have messed up my system. I am working on weening off, I am down to an OTC Zegrid and I feel improvement.
GERD Moderator; Diagnosed GERD, no other medical conditions (this one is enough) ; Gluten free since 2012; low lactose since 2012

jon c.
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Date Joined Feb 2014
Total Posts : 1
   Posted 2/1/2014 5:14 PM (GMT -6)   
I have recently been diagnosed with a small hiatal hernia and was put on hi probiotics and 40 milligrams protonix. My reflux I seem to stay the same, I don't eat wheat very little alcohol consumption, no smoking and I juice almost everyday. I myself and no questioning PPI's are causing more acid reflux due to the fact that I might have low acid production to begin with. In my upper and oscopy the pictures seems to show very little stomach acid when I had fasted for 12 hours prior to which makes me believe that I have low stomach acid and almost zero now on PPI's.
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