I don't take Nexium but I do take another PPI Prevacid. I asked my doctor the same thing about
my med because that is what the insert said on my medication but he told me that it really doesn't matter, that the benefit to it is it allows your stomach pumps to shut down before a meal so the meds are most effective but I never remember to take it 1 hour before a meal.
I don't know if Nexium has them but Prevacid has the solutabs that now make it uneccessary to wait an hour.
IBS, Diverticulosis, GERD, Disc Degeneration
"If you don't like something change it; if you can't change it, change the way you think about it" - Mary Engelbreit