switching PPis ineffective? help- considering LINX surgery but want second and third opinions...

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Regular Member

Date Joined Mar 2013
Total Posts : 174
   Posted 6/5/2013 6:26 AM (GMT -6)   

For the last month I've had a GERD flare after switching birth control pills (I have since gone off hormonal BC altogether) and have not been able to get ahold of it since. At the time of the flare, I had been taking 20 mg of omeperazole with good result, but after the BC pill switch caused a GERD explosion, even when I doubled my dose to 40 mg and even when I switched to 40mg of a different PPi, pantaprazole, I am still getting frequent, painful heartburn. It's been over two weeks since I switched to 40 mg of pantaprazole and I have added 3 150 mg zantac a day on top of it. Still heartburn.

Desperate, I did a consult with a surgeon who told me that studies seem to show that after a point, PPis simply stop working, and when that happens, switching PPis won't do much or make much difference and that I am screwed. He said my body had either figured out a way around PPis or I was suffering from bile reflux. He didn't have an answer about why birth control pills would have sparked it off.

I am seriously considering the LINX. I am 29 years old and do not want to be on PPis forever, especially if said PPis are not working very well or at all. BUT I wouldn't mind delaying the surgery for a while to give surgeons more of a bank of experience to draw from when it comes to LINX before getting one myself.

Is it true that switching PPis may be a waste of my time? Two of them, anyway, have failed to work almost entirely at 40 mg...

Thank you for your help,


Regular Member

Date Joined Mar 2013
Total Posts : 174
   Posted 6/5/2013 6:27 AM (GMT -6)   
PS it's been two months since the flare started.

(I hope it's a flare and not my new, permanent state of being)

Veteran Member

Date Joined Apr 2012
Total Posts : 707
   Posted 6/5/2013 7:48 AM (GMT -6)   
Switching ppi's isn't always a failure, sometimes you get lucky and find one that works (may not last forever). I was on 2x daily ppi's at one time and only felt worse when doing so. To be honest, if I was to have a surgery, I would opt for nissen over any others (it's been around for 60+ yrs vs LINX that I'm not sure anyone has had more than 5+ yrs).

Elite Member

Date Joined Apr 2007
Total Posts : 32602
   Posted 6/5/2013 8:56 AM (GMT -6)   
Grover Cat,
Sorry to read you are continuing to have problems.  I see you found the LINX Thread as the members of that thread know all about LINX.
Also we have members that have had the LINX Procedure and I am sure you will be hearing from them.
Moderator: Anxiety, Osteoarthritis,
GERD/Heartburn and Heart/Cardiovascular Disease.

"The wind blows, the sun rises, the snow falls and the ocean relentlessly pounds the shore. Life rolls on with fresh new possibilities at every turn."

Regular Member

Date Joined Mar 2013
Total Posts : 174
   Posted 6/6/2013 8:39 AM (GMT -6)   
Thanks for all your advice. It's certainly disheartening to have the PPis suddenly fail me. I'm definitely willing to go for surgery to fix this as a last resort, but I just had some slow healing oral surgery, and going under the knife again is not top on my list for a few months anyway.

Today I've started trying Pepsid Complete instead of Zantac... any thoughts on OTC supplements to PPis? I've heard some good things about Gaviscon too but have never tried it yet.
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