ECM scaffolds are now being increasingly used in all types of surgery, from vascular repairs to skin grafts, heart valves and soon to start clinical trials of replacement meniscus.
Look at some of the work being done in the US by one of the pioneers of ECM's. [Stephen Badylak]http://www.mirm.pitt.edu/badylak/projects/Esophageal_Tissue_Engineering.asp
There are biotechnology co's in the UK and US looking to commercialise these applications in the near term. ECM's are classified as medical devices and as such have a very short time from concept to market.
In the UK the company Tissue Regenix has a world beating process for the preparation of ECM'shttp://www.tissueregenix.com/
The benefit of this technology is that it relies on the bodies natural repair mechanisms, to cause a kind of stem-cell homing, that over a short time replaces the scaffold. This means that there is little chance of infection and no need for anti-rejection medicines.