never heard of LPR before - thanks for posting. i've been diagnosed with barrett's oesophagus and GORD and am on Nexium 40mg in the am and 20mg at night. Keeps it under control mostly but i also have nasal polyps and chronic rhino-sinusitis. i'd read somewhere that the acid can trigger that, but didn't realise it was actually a condition that is recognised as causing it specifically. it explains the horrors i've experienced on aeroplanes before and after diagnosis, and in elevators and on public transport. not so bad now for the latter, but haven't been on a plane since it was diagnosed - when it was diagnosed i couldn't even walk at times or even catch a bus for a short distance, let alone drive. it was really bad. 2 years later, no ciggies, no alcohol, plenty of vegies and fruit and exercise and the aforementioned nexium and i'm on the mend, but still have a little trouble at times with a raspy throat and blocked sinuses, so am a little anxious about jumping in a tin box and the changes in air pressure at altitude. figure a 1 hour trip should be ok so long as nexium is taken, mostly empty stomach, chewing gum and sudafed is on board, as well as some ventolin cause the acid gets into my lungs too which is very annoying and makes breathing hard at times.