Omeprazole and Swallowing Difficulty?

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New Member

Date Joined Sep 2013
Total Posts : 2
   Posted 10/1/2013 11:27 AM (GMT -6)   
Hello All - New here, but I've been coming here for info and experiences ever since I was diagnosed with gastritis / small ulcers / duodenal inflammation and h pylori after EGD.

Before I was diagnosed, I experienced severe stomach pain, bloating, appetite loss. Was prescribed triple therapy (80 mg omeprazole, amoxicillin, clarithromycin) for 14 days. 5th day in, had a nasty response to the clarithromycin that closed down my throat, making it difficult to swallow even water. Dr. said to keep with 40 mg omeprazole (20 mg day/night) and discontinue the antibiotics.

After about 3 weeks from that episode, had another EGD and h pylori was eradicated. Small ulcers and duodenal inflammation also gone, and gastritis was now just mild. Dr. said to continue with the 40 mg omeprazole for up to 8 weeks.

It's been about 3 weeks with the omeprazole (last week at 20 mg/day at my request approved by dr.), and I am having great difficulty swallowing. And since my gastritis has improved, pylori eradicated, etc., I can't figure out why it would now be difficult to swallow after all of this time. Feels like gas pressure pushes food (and liquid ) upwards most of the time (or things just sit in the stomach and it bloats). Food moves slowly down the throat. Also burning sensations in chest when swallowing certain things. I can only think it's related to the omeprazole.

Has anyone experienced this from omeprazole? I didn't have this as one of my symptoms pre-treatment. Dr. said i could discontinue for a few days to see how I feel, but does not recommend discontinuing it medically until gastritis all clear. Seeing my GI later this week. Feeling weak from this all-liquid diet...Thank you.

Forum Moderator

Date Joined Feb 2009
Total Posts : 7188
   Posted 10/1/2013 12:25 PM (GMT -6)   
Hi Stayup,
What it sounds like is an esophageal reaction to reflux.  When you have reflux that persists it can create that type of swallowing problem.  I'm no doctor, so I'd recommend you follow up with him/her regarding this issue.  I rather doubt it has anything to do with the omeprazole, but your doctor may want to change the medication you're on.
Best wishes,
GERD/Heartburn Moderator
Nissen Fundoplication 2/09

"Whatever you fight, you strengthen, and what you resist, persists.”

“Worry pretends to be necessary but serves no useful purpose”

“Accept - then act. Whatever the present moment contains, accept it as if you had chosen it. Always work with it, not against it.”
Eckhart Tolle

New Member

Date Joined Sep 2013
Total Posts : 7
   Posted 10/1/2013 2:32 PM (GMT -6)   
Hi Stayup,

I have had the exact same symptoms as you .....throat almost closed up...every time I eat..whether it's food or would pool in my throat....I went off of my protonix...almost two weeks now...and as each day goes by I am getting better and better. I had to be put on anxiety meds...lost almost 15lbs due to not being able to eat. But now I don't eat after 6 or 6:30 a bland diet....turkey, chicken, pork...hardly any red meat. No soda or fruit juices...just water and tea (hot or cold)....once in a while I have to take a sip of Mylanta....I even sleep with one pillow now without the acid coming I must be doing something right. Been doing a lot of reading on GERD and some doctors say that the medicine can be dangerous to certain people. It was originally meant for people to heal approximately 6 or 8 weeks....unfortunately there are a lot of people that can't be without it....I'm hoping that I am not one of them. So far so good!


New Member

Date Joined Sep 2013
Total Posts : 2
   Posted 10/6/2013 12:18 AM (GMT -6)   
Hi Denise - Thank you very much. I think you're right re: esophageal reaction to reflux, and it is also impacting my throat (very irritated) and ears (sometimes irritated)...

Barbara - I'm off the omeprazole, will be a week tomorrow. Swallowing has improved tremendously since, so that's progress. I've lost way too much weight. I'll be following a diet similar to yours very shortly (I'm not eating anything "bad" right now, just haven't been eating anything, so, I guess I am looking forward to graduating to the bland!). Glad to hear things are going well!

Have a follow up appointment next week. Experiencing mild gastritis symptoms, but need to address it differently now because the powerful drugs just don't seem to work for me. I think they actually made me worse off, so I'm wary.
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