A new take on acid reflux

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Regular Member

Date Joined Sep 2013
Total Posts : 262
   Posted 10/16/2013 2:19 PM (GMT -6)   
Through previous research I have learned that the amount of acid that is secreted into the stomach after eating food is based on the gastrin levels in your body. Taking any sort of antacid, H2 blocker, or PPI will increase your gastrin levels as your body tries to counter the effect of those by thinking it needs to produce more acid for breaking down the food. As we know, this is what causes acid rebound when coming off of H2 blocker and PPI medications.
After thinking on this for awhile I was wondering if through long term eating habits, you can get the same effect without taking medications which in turn can cause some of the same problems so I did a little research on the effect of gastrin levels based on different foods. In doing this I found an interesting study (http://gut.bmj.com/content/12/8/619.full.pdf). The study proves that the theory I have is correct in that different types of foods will promote your body to produce more acid to break it down. The longer you eat those foods the more gastrin your body builds up in order to keep up with your eating habits. When making a change in your diet, your body needs to adjust and in doing so, you may get a little acid rebound without thinking that you have acid rebound because you weren't taking any medications.
Keeping this in mind, it becomes very important to follow strict eating habits to try and maintain the same gastrin levels. The overall idea here is to maintain a healthy life style without any drastic changes that effect the overall ecosystem of the body.
So in conclusion, by eating what your body needs (equal sized meals throughout the day, every day), you can maintain proper gastrin levels. I'm not sure how long one would need to eat large meals (days, months?) to experience a rebound effect when going back to smaller meals. But it is something to think about. A major key to help with heartburn is to understand the science behind how our body works so we can understand and know how to get it to function the way we want it to based on our actions.

Regular Member

Date Joined Jun 2013
Total Posts : 28
   Posted 10/17/2013 9:12 PM (GMT -6)   
Ii couldn't get your link to connect; but this info is very interesting and I will look into it.

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Date Joined Apr 2007
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   Posted 10/18/2013 11:01 AM (GMT -6)   
Thanks for the link, however, without a degree in science I was floundering as I waded through the information.
Also the article was published in 1971  (42 years ago).
I admire you for your diligence in looking for information that agrees with your theory.
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GERD/Heartburn and Heart/Cardiovascular Disease.

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Regular Member

Date Joined Jul 2012
Total Posts : 190
   Posted 10/18/2013 11:12 AM (GMT -6)   
Hi javery,
Thanks for the link. I agree with Kitt that it was quite technical.
Assuming in the time since the report was written this information about Gastrin levels has not changed it is interesting and relevant to refluxers. The information could be very useful to those reducing their ppi, as for example they could reduce protein intake to help reduce rebound.

Veteran Member

Date Joined Apr 2012
Total Posts : 707
   Posted 10/18/2013 11:19 AM (GMT -6)   
To all,
I disagree with the findings in this report. My reflux is better with protien intake and worse with fat or carbs but maybe thats just me.

Veteran Member

Date Joined Apr 2011
Total Posts : 1604
   Posted 10/19/2013 6:27 AM (GMT -6)   
It is an interesting thought - I wonder if I sometimes make myself worse by constant snacking, but then sometimes that's the only way I can cope so it's a vicious circle. Wonder what effect chewing gum has on gastrin levels??


Regular Member

Date Joined Jun 2013
Total Posts : 28
   Posted 10/19/2013 6:47 AM (GMT -6)   
Snacking helps me too. We might end up getting back to the idea that every body is different. However the idea of six small meals makes a lot of sense. When I have eaten too much or too many different foods at a time I have definitely regretted it.

Veteran Member

Date Joined Jun 2011
Total Posts : 795
   Posted 10/19/2013 1:07 PM (GMT -6)   
Small frequent meals are very important in reducing pressure on the LES. Both fats and many carbs increase heartburn, according to a recent article published by the Mayo Clinic. A single study never proves anything, and if there is nothing more recent supporting its conclusion I would doubt it's current validity.

Post Edited (sunbeam48) : 10/19/2013 1:10:20 PM (GMT-6)

New Member

Date Joined Oct 2013
Total Posts : 1
   Posted 10/20/2013 11:55 PM (GMT -6)   
Before taking any medication make sure your body is well hydrated throughout the day - I sorted out my problem with drinking enough water during the day. Start by drinking 2 glasses in the morning - I am sure some people's symptoms will clear by doing this.

Also, slippery elm seems to be working on some people. There's a post here about it-


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Date Joined Mar 2012
Total Posts : 1110
   Posted 10/21/2013 11:26 AM (GMT -6)   
I alaso do better with lean proteins and easy to digest carbs.
GERD Moderator; Diagnosed GERD, no other medical conditions (this one is enough) ; Gluten free since 2012; low lactose since 2012
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