Rebound after missing one dose? Is that possible?

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New Member

Date Joined Dec 2013
Total Posts : 3
   Posted 12/9/2013 2:55 AM (GMT -6)   
I was told I had LPR a few years ago and went on a short stint (2-3 weeks) of ppi's and was able to go off them without any problems. A recent endoscopy showed I had grade 2 esophogtis (even though I don't get heartburn) so my GI put me back on 40mg 2x a day. I've been on them for only 3 weeks and forgot to take a morning pill while vacationing in Mexico and by that evening (a few hours after I took my evening dose) i got rebound so bad that it felt like a fire ball came up into my throat. It resulted in bad laryngitis, a horrible cough, painful swallowing, phelgm, etc. I never experienced anything like it in my life and thought if these could do that with just missing one dose after 3 weeks how will I ever get off these pills in 2 months. Does this sound normal......I wouldn't think these are safe to prescribe if this can happen by only missing one dose.

Feeling like I caused more damage than I already had

Elite Member

Date Joined Apr 2007
Total Posts : 32602
   Posted 12/9/2013 5:22 PM (GMT -6)   
Hello and welcome to HealingWell.  I have read that missing a couple doses of PPI can cause an increase in acid production and rebound of severe symptoms.  It is possible that is what happened even after missing only one dose.
Hopefully another member will be along to help with your question.
Moderator: Anxiety, Osteoarthritis,
GERD/Heartburn and Heart/Cardiovascular Disease.

"She Stood in the Storm & When the Wind Did Not Blow Her Away, She Adjusted Her Sails."
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