Nexium/carafate affecting asthma?

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ReneeS
New Member


Date Joined Jan 2014
Total Posts : 12
   Posted 1/28/2014 6:50 PM (GMT -6)   
Hi, i know this area is for GERD and reflux but I wasn't sure where else to post this and I know many of you take these same meds. I was put on Nexium and liquid carafate for an ulcer a week ago. I am now having problems with my asthma acting up almost continually. I stopped the Nexium two days ago but it still continues. Has anyone else experienced this? Thanks.

mudmagnetmum
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Date Joined Apr 2011
Total Posts : 1604
   Posted 1/29/2014 4:22 PM (GMT -6)   
Hi Renee

I'm sure Denise will be able to help you out here....... but in the meantime..........

GERD and asthma are very much able to annoy each other. Reflux can irritate the airways and asthma medication (the long acting Ventolin LABAs) can relax the LES and increase GERD symptoms. Also, I guess the constriction and squeezing that goes on during an asthma attack can possibly also increase reflux.

In your case is it possible there's something in the medication you are reacting to? Can you try Zantac instead? Did you try Nexium on its own without the Carafate? Did you go back to the doctor or telephone to say you have increased asthma symptoms since starting the treatment for the ulcer?

Usually controlling reflux symptoms would help asthma, so I'd be wary of not following through for the ulcer treatment, but I would see if you can pinpoint whether it's the Nexium, the Carafate or just a coincidental flare up of your asthma.

I had trouble myself with many of the PPIs due to my allergies and one thing I did notice is that apart from Lansoprazole they all contain colourings. Pantoprazole is blue - how healthy is that?!

MMM
GERD (3 years and counting)
Lifelong stuff: Food allergies/intolerance, eczema, asthma

ReneeS
New Member


Date Joined Jan 2014
Total Posts : 12
   Posted 1/31/2014 1:42 PM (GMT -6)   
Hi MMM,
Thanks for responding. I don't suffer from GERD or reflux, I was tested for it and it came back negative. That's why I said I knew I should have posted on another page but wasn't sure where and since so many from this page take the same meds I took a chance that I might find help here.

I was on Zantac for 9 months or so and got no relief I also used PRilosec, same result. I did go back after you asked and tried the Nexium on its own. That is what is causing the asthma flare ups. Thank you for your help. I hadn't considered that it might be the coloring in it but after you mentioned it I started wondering. While in the hospital I had an allergic reaction to the iodine dye I was drinking before the CT scan. They said it almost never happens and I've never had a reaction to a medication before. I'm beginning to suspect there may be a correlation. Maybe I'm becoming more sensitive. Again I appreciate your thoughts. I'll have to discuss it with the doctor to see what she thinks. It's good to have this forum to bounce ideas around. Btw, I'm back on the Carafate and having no problems. Yea and thank goodness. :)

mudmagnetmum
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Date Joined Apr 2011
Total Posts : 1604
   Posted 1/31/2014 1:58 PM (GMT -6)   
Hi

Glad you've made some progress! Maybe they'd let you try Lansoprazole - at least that comes in a white capsule!

Have they ruled out Helicobacter as a cause of the ulcers?

Apologies for the confusion regarding reflux but glad to have been of some help!

MMM
GERD (3 years and counting)
Lifelong stuff: Food allergies/intolerance, eczema, asthma

dencha
Forum Moderator


Date Joined Feb 2009
Total Posts : 7181
   Posted 1/31/2014 3:20 PM (GMT -6)   
Hi Renee,

Sorry to hear your asthma is kicking up! As a fellow asthmatic, I know how hard that is. You said you were tested for GERD...what tests did you have, and what were the results?

I have always had the experience that when my stomach is bothering me, I get increased reflux, and my asthma kicks up. My GI doc did 24hr PH monitor on me and got a score/DeMeester score of 4, and he told me with certainty that my reflux was not causing my asthma to be worse.

That was certainly not my experience. My PCP and asthma docs were certain it was. I just give you that information because it is likely similar to your experience...the test score did not demonstrate what was really going on.

My asthma doc says that most GI docs have no idea how a very little amount of reflux can dramatically affect the lungs. Eventually, at the constant insistence of my PCP who was trying to keep me breathing, I had additional tests, and got a DeMeester score of just over 14. 14 is considered the top of the "normal" range.

After constant prodding from my PCP, the GI doc FINALLY sent me to a surgeon, and three weeks later I had the Nissen fundoplication surgery. After about 2-3 months, my lungs healed and I'm doing great. I'm 5 years post op, and while I do get allergic issues/sinus issues that can affect my lungs, it's NOTHING like it was prior to surgery.

I'm not saying you need surgery. I suffered with HORRIBLE out of control lung issues--using my nebulizer several times a day/taking high doses of steroid inhalers and sometimes Prednosone, for about 6 years. What you're experiencing is much less severe. Still, don't assume that if the GI doc assures you that you're not having reflux, it doesn't mean you're not having enough reflux to cause your increased asthma symptoms.

As MMM says, be sure to take your PPI consistently. For many years (probably 15 or so) the PPIs did the trick, and my lungs were basically fine, as long as I didn't take an antibiotic and get my stomach percolating acid, which always, always, always, caused my asthma to go off the charts. Once I was even hospitalized because of it.

I have a very sensitive stomach, and LOVE Carafate suspension. It has been a lifesaver...especially when I have a flare/gastritis, and before my surgery, it helped greatly with esophagitis pain. While anyone can be allergic to anything, I've never had a moment of trouble with it. I still keep it on hand at all times, because my stomach is reactive, and every so often it starts complaining. The Carafate really protects it and makes it feel better.

I don't know if this response helps at all, but if you have any questions, ask away!
Best wishes,
Denise

GERD/Heartburn Moderator
Nissen Fundoplication 2/09
Allergy/Asthma

"Whatever you fight, you strengthen, and what you resist, persists.”

“Worry pretends to be necessary but serves no useful purpose”

“Accept - then act. Whatever the present moment contains, accept it as if you had chosen it. Always work with it, not against it.”
Eckhart Tolle

ReneeS
New Member


Date Joined Jan 2014
Total Posts : 12
   Posted 1/31/2014 5:54 PM (GMT -6)   
Hi MMM and Denise,
They said the blood test was neg. for H. Pylori.

The test they did for reflux was a barium swallow. I hadn't heard of anything else. I was originally given Protonix for my ulcer before the Nexium but it made my heart pound like crazy so we switched. Now this. And I only got one script for Carafate with no refills. When I call saying I have problems it's like I'm causing problems. At this point frankly, I'm ready to just give up. It's all so frustrating. (But too painful to give up. Sigh.....) thank you both for your input.

dencha
Forum Moderator


Date Joined Feb 2009
Total Posts : 7181
   Posted 1/31/2014 11:02 PM (GMT -6)   
Hi Renee,

If you've found the answer to your asthma issues, great! There are lots of options out there, so hopefully you'll find a PPI that works for you, and doesn't cause problems.

I understand your frustration. My first GI doc was downright rude when I asked him for advice on a problem I was having (selecting an antibiotic that might not be as hard on the stomach), and finally I'd had enough, and fired him. I asked my PCP to recommend someone who would really listen, and hear what I was saying. He did, and my new GI doc was great. Unfortunately, I've since moved, and haven't found another one like him yet.

The barium swallow can show obvious reflux and the presence of a hiatal hernia, which is often a trigger for reflux. That said, you can reflux in a way that doesn't show up on a standard barium x-ray. They can do the test with other barium concoctions (with lighter-weight liquid and even carbonated swallows, etc.) that might give additional information.

It's a great, non-invasive test of swallowing abilities, can diagnose a hiatal hernia, as well as obvious reflux. Do you suspect reflux? It may have absolutely nothing to do with the problem you're describing, but it's extremely common for asthmatics to have reflux. Just an FYI, to be aware of.

Good luck getting things healed in your stomach. It takes a lot of patience, I know. I was never diagnose with an ulcer, but my reactive stomach caused tremendous pain, and the esophagitis caused by the reflux was even worse.

Hope you feel better very soon!
Best wishes,
Denise

GERD/Heartburn Moderator
Nissen Fundoplication 2/09
Allergy/Asthma

"Whatever you fight, you strengthen, and what you resist, persists.”

“Worry pretends to be necessary but serves no useful purpose”

“Accept - then act. Whatever the present moment contains, accept it as if you had chosen it. Always work with it, not against it.”
Eckhart Tolle

ReneeS
New Member


Date Joined Jan 2014
Total Posts : 12
   Posted 2/1/2014 9:37 AM (GMT -6)   
Hi Denise,
I've never had any symptoms of reflux that's why I believed the test results it was yet another test I felt was unnecessary that was insisted upon. The dr. Said because I cleared my throat I must have reflux. I tried to explain that it was the asthma and that I was trying to stop myself from coughing (the air in the office always makes me cough like crazy so to hold it off I clear my throat or I won't be able to stop coughing) I didn't even know there were other tests available.

I'd like to find a dr. who will work with me on what tests we both agree are necessary. I don't like feeling like I'm going to be dropped if I don't go along. I'm thinking it's time to find a new dr.

Thank you for your help. It was very appreciated.
Renee

mudmagnetmum
Veteran Member


Date Joined Apr 2011
Total Posts : 1604
   Posted 2/2/2014 7:14 AM (GMT -6)   
Hi Renee,

It is possible that you don't have reflux. It's also possible that, like me, you have a small amount of reflux which your body reacts violently too. However, what they have seen is the ulcers, and it's unusual to have ulcers that aren't the result of helicobacter infection, except in people who are on heavy duty drugs like the cytotoxic ones... as far as I know at any rate.

Helicobacter can escape detection and the best test is biopsy during endoscopy e.g. You can have negative stool or breath tests and positive biopsy. I would ask what they believe the cause of your ulcers is and whether or not you would benefit from a more thorough screening.

Meanwhile keep going with whichever treatments make you feel better and of course acid suppression will help ulcers to heal - and there's always Zantac if the PPIs cause you too much trouble. Let us know how it goes!

MMM
GERD (3 years and counting)
Lifelong stuff: Food allergies/intolerance, eczema, asthma

ReneeS
New Member


Date Joined Jan 2014
Total Posts : 12
   Posted 2/25/2014 6:44 AM (GMT -6)   
Hi,
Just wanted to post an update and to also thank you both for all of your help. It was very frustrating to be in so much pain and to not be able to think clearly or to turn to the doctor for help. I finally felt the need to really do some research myself and turned to natural alternatives. I began taking a product called CarnoSoothe. I researched it and chose it because in their own words it " naturally modulates the growth of H. pylori while supporting the health of the gastric lining." It contains different supportive extracts that I researched beforehand and was comfortable with and felt were safe which was something I couldn't say about the Nexium after reading about it's long term effects. I also began taking a high quality aloe called TrueAloe from NatureCity.com twice a day. These two products along with zantac twice a day and cutting back to almost no caffeine has helped a lot. I'm still having a few days of pain but it is so much better that I don't notice it much. It is only in the last week that I can say I only have mild twinges. I am able to eat and am putting on weight again. I think it was worth the research and time invested. Thank you for all of the time you both put in to helping me. It was so appreciated.
Renee

mudmagnetmum
Veteran Member


Date Joined Apr 2011
Total Posts : 1604
   Posted 2/25/2014 7:01 AM (GMT -6)   
That's great to hear Renee, well done! CarnoSooth sounds nice - I'll look into that one!

I'm currently doing "mindfulness" (guided meditation) which has been shown to help with pain (I have hypersensitive oesophagus) - seems good for redirecting the mind so you're not constantly checking your symptoms and pain levels!

A few new comers have been asking about natural remedies - you might like to post on one of those threads too.

MMM

ReneeS
New Member


Date Joined Jan 2014
Total Posts : 12
   Posted 2/25/2014 7:22 AM (GMT -6)   
Where do I find the thread to post to?

mudmagnetmum
Veteran Member


Date Joined Apr 2011
Total Posts : 1604
   Posted 2/25/2014 11:02 AM (GMT -6)   
www.healingwell.com/community/default.aspx?f=45&m=2995324

There are several and one in particular got flooded with a long list of impractical suggestions! Try this link to a more recent one.

MMM
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