Here's the catch 22 in all this.
Most bacteria can't live in a stomach with the proper Ph of 3-4.
People taking PPIs or other acid suppressing drugs have stomach Ph much higher than that.
Bacteria will then thrive in your stomach and the first part of your small intestine.
The bacteria have a feast working on the carbohydrates you eat, fermenting them like crazy.
That process causes gas, belching, that bloated feeling, and contributes to the wind out the other end.
As jamosca said, if you have h. pylori or candida, a course of antibiotics might be necessary. But as Teacherman mentioned, you should also be taking a pro biotic to replace the good bacteria that will be killed. PPIs so mess up your digestion, that I would also take a digestive enzyme like Digest Gold. That alone has reduced my gas.
It starts a vicious cycle when you try to reduce stomach acid, and the only way to get out of it, is to get off the acid suppressing drugs. Until that happens, the best thing you can do to make life less windy is alter your diet to remove as many carbohydrates as possible. No more sugar, high fructose corn syrup, only fruits with low fructose content (Google for a chart), eliminate almost all grain products. It's almost like going on a Paleo diet.
There's an interesting book that explains this called Fast Track Digestion, by Norman Robillard. He was a heartburn, GERD, and reflux sufferer, who figured out how to pretty much cure it with dietary changes. The first half of the book is the science behind his method. The second half is full of meal plans and recipes. It may not work as a cure for everyone, but it should definitely cut down on the gas issues. And for many of us in this boat, the gas is actually causing the reflux.