I totally relate to your frustration. Over a six-year period I had all the usual tests my GI could think of but could not prove reflux. I then went through the same thing with a second GI with the same result. Then saw various specialists and recently saw an ENT specialist who carried out a nasal scope exam and saw inflammation and scarring of the larynx area. She asked me if I had ever had my adenoids out which I haven't. She went on to say "that's odd because I can see scarring, something I have never seen in a patient". She then conferred with my GI and between them decided to refer me to a general surgeon.
The surgeon studied my very long list of tests and then asked if I had ever had a barium meal test. I replied that I had not. He sent me for the barium test but requested that the radiologist call him immediately before he carried out the test so that he could "direct" the test. He had the radiologist have me lay on my back, slightly to the side on the x-ray table.
Next he asked me to drink the barium meal, waited a little while and then tilted the table back so that my head was lower than my feet. This brought me to the end of my six-year search to prove reflux when all along I was certain it was taking place. The radiologist informed me then and there that he could see the barium meal traveling out of the stomach and all the way up to the very top of the throat. With this long sought after medical confirmation, the surgeon was able to offer me Nissen Fundoplication surgery if I wanted it.
I have set up an appointment to see my Gi again after the surgeon suggested getting his opinion on these findings and perhaps carrying out another endoscopy (my 4th to date) to see if the gastritis, stomach inflammation and lower esophageal inflammation has improved or worsened since the last endoscopy.
After six years on and off PPI's and H2 Blockers, it has not produced any noticeable healing - the stomach pain and internal burning is as strong as it was six years ago. I have not been able to sleep through the night for those six years due to the fact that the stomach pain wakes me every time I turn on either side, or my stomach - I am totally sleep deprived and exhausted by what seems like a very, very long journey.
Incidentally, my diet has been beyond reproach throughout this time and long before that, supervised by one of this country's leading experts on nutritional science - he is also my primary care physician.
Hope this helps in some way.
Post Edited (Rayday) : 3/18/2014 4:10:34 PM (GMT-6)