Edited: LPR/LSN Doing much better, sharing experiences

New Topic Post Reply Printable Version
36 posts in this thread.
Viewing Page :
 1  2 
[ << Previous Thread | Next Thread >> ]

Ying
Regular Member


Date Joined Sep 2015
Total Posts : 63
   Posted 3/8/2016 7:42 PM (GMT -6)   
What does the z line mean? I went on vacay and my symptoms got much better. When I returned last night suddenly I started coughing again. Today I've been having a lot of neck pain again 😱😭

albertocastillo2001
Regular Member


Date Joined Apr 2014
Total Posts : 53
   Posted 3/10/2016 3:40 PM (GMT -6)   
Stress is a real trigger for this as many people have reported..

I know it's difficult but try to stay relaxed as you keep trying things. Do your best to stop that cough

I am also over stressed with this and that's a real known factor for reflux as well.

Irregular Z line. It's the line that separates the stomach from the esophagus. Mine semes to be irregular. There are lots of comments on the net saying that this is associated to barret esopphagus, but it's also found on healthy people. A biopsy was taken so we will see... I hope there's nothing to fear about.

Thanks

albertocastillo2001
Regular Member


Date Joined Apr 2014
Total Posts : 53
   Posted 3/30/2016 2:29 PM (GMT -6)   
Hello again

I received my peptest samples results. Took them like one after waking up in the morning, and the other 2 one hour after a meal.

I got one high sample and two moderate samples. I assume the high sample was the one taken in the morning.

The day I took them I was like perfect in the morning as far as I can remember and I don't remember having too many symptoms that day.

As I told earlier. PPIs didn't work for me (althought I was only on omeprazole). And I really improved with an anti depressant.

I do believe that pepsin might be a contributing factor for some people, but not for others. What I still firmly believe it's my issue is my high sensitive throat (LSN/PVVN) after my throat infection.

Besides that, see this article and get your own conclusions:


The way I understand it is that even the healthy patients had pepsin. Maybe on a lower concentration that the ones with reflux but doesn't seem like that much. Plus there's also this other article:
http://www.webaigo.it/download/salivary%20pepsin%202015.pdf
Indicating this text:
Pepsin can be found in saliva in healthy subjects
and patients with heartburn, particularly during
postprandial periods. Up to 1/3 of healthy
asymptomatic subjects may have pepsin in saliva,
but nearly all at concentrations below 200 ng/mL


Pepsin is found on many different levels on healthy patients as well. So I am unsure if Pepsin alone can confirm the existence of our throat issues as some users reported they are better after eating or in the morning.

My symptoms still keep getting better apparently. There are fallbacks tho, but never linked them to eating. And I am sure the pepsin level is the same as in the beginning, or even before my disease started before the virus infection (But I can't measure it now). I have no made dietary changes. But I will start doing them now. Althought I am mostly following a good diet most of the time.

I assume that pepsin (any kind of reflux) and allergies might be an agravant in my case.

Thanks

Post Edited (albertocastillo2001) : 3/30/2016 2:35:37 PM (GMT-6)


Hopefull12
New Member


Date Joined Mar 2016
Total Posts : 3
   Posted 3/31/2016 9:09 AM (GMT -6)   
albertocastillo2001 said...
Hello everyone

I really hope you all are better. I improved greatly and I wanted to contact everyone who I sent a message to to share my experiences.

I've been posting mostly on another forum so I will copy the same progresses here and I hope it becomes useful for all of you:

"In April 2010 I got an upper repisratory infection (tonsillitis) and since then I had a big globus feeling on my throat, painful swallowing, constant mucus on throat that felt like post nasal drip but I was unable to swallow it, tight throat and constant cough.
After a year later it got worse from so much coughing and I began to feel wheezing sounds and some needle/pins/cold/burn pain in the right side of my throat and chest. (Something similar to the pain you feel when you have slept over your arm and not enough blood is going thru it)
Most of all the symptoms I had were mostly felt in the right side of my throat and would feel much worse on Winter. All colds would turn into bronchitis

I have been diagnosed with asthma, reflux, lpr, allergies, rhinosinusitis, psychological..... bla bla bla.
After reading here a few months ago, and thanks to the invaluable help of Seeking Sunrise, LPR Slayer, Kevinla, peebles, lprclark, gpinzone, LPR1978 and probably others I didn't mention and the articles I found after related to PVVN and LSN I managed to discover that my problem was related to this LSN/PVVN, irritable larynx syndrome issue.

I've been treated with ppis, nasal steroids, antihistamines, etc, and none worked. Only two shot of Trigon Depot, a really strong corticosteroid helped for one month.

All I can tell you is that this disease is really unknown for doctors. They can't understand it. I figured that if they don't know what your problem is, they will say it's a virus, it's psychological, it's an autoimmune disorder. In short words, they won't ever recognize they don't have any freaking idea of what's going on. I think I went to 20 different doctors.

Since June I started taking Besitran, (Sertraline, known as Zoloft in USA), a soft antidepressant, due to a "system shutdown" caused by amitriptiline.
I began with 50mg of Besitran and increased it to 100mg next month. In one month and a half I began to feel improvement, my need to cough reduced, althought I still needed to clear my throat and had some difficult swallowing pain sometimes.

Since then it has been improving, I must say progress is really slow, but it works. I am much better now. I also started doing acupuncture 2 months ago and it seems it helped as well. I am also taking a homeopathic remedy called "calcarea carbonica", I think this one is not doing much, but anyway.

My progress hasn't been always straight, sometimes I would go backwards, but it would improve over time, like going upstairs.

At the moment I actually don't cough much, sometimes I still need to clear my throat, but it's really much less than what it was before and also feel wheezing, but I think it's quieter. I think some foods swell my throat. I never did any reflux test, except a barium swallow which seemed fine. My voice is slightly raspy but it seems issues have moved to the center of the throat so I think I only have swollen tissue which should heal over time.

Another thing I want to tell everyone is that doctors will mainly focus on stuff due to what they see in your history. It seems like when you're flagged as an allergic or sinuses, you can't get out of there and doctors won't ever look any further. In my case they always looked at my nose instead of listening to me.

I hope this is useful for anyone, feel free to ask me whatever you need to. This disease can be cured. I hope I can send hope to everyone who is suffering about this.
It's not life threatening, but it really diminishes your quality of life."

Take care

albertocastillo2001
Regular Member


Date Joined Apr 2014
Total Posts : 53
   Posted 3/31/2016 11:02 AM (GMT -6)   
Hopefull12. Did you mean to write something? I just see my quote :))

albertocastillo2001
Regular Member


Date Joined Apr 2014
Total Posts : 53
   Posted 4/8/2016 1:43 PM (GMT -6)   
I got the results of the gastroscopy and the biopsy.

There's nothing to feat. The Z had no sign of inflammation. Which means that I probably was born this way or the chronic cough lifted my stomach up. The duodenum is perfect and the stomach seems to have a really low grade chronic inflammation. We don't know the cause but nothing to fear of.

I do feel my LSN has improved recently a bit more.. But still. I am so tired of it and wonder if it will ever dissapear.

albertocastillo2001
Regular Member


Date Joined Apr 2014
Total Posts : 53
   Posted 5/19/2016 6:21 AM (GMT -6)   
Hello

I think it's time for another update
I do feel I am still improving. Throat clearing is quite non existing on some days. Swallowing seems mostly fine, hardly any globus feeling. Still problems on the right side of my throat, that are not too bothering anymore but are still there.

I saw a physiotherapist a month ago who helped with some back and neck pain and I do feel it has relieved me overall. I expect to see him again next week. I am also still going to acupuncture.
I also had a neck CT scan which came back fine.

I also have started gabapentin on Friday. So far i don't seem to have any side effects.
I started 300mg on Friday and today I took my first double dose, 600mg. One at night, one in the morning. We don't know if I will need to raise it up to 900mg. I am not sure if I have felt any improvement. But I think my wheezing sounds different, like the sound is lower. I really can't say if it's because of the gabapentin or not. I will need to wait a few weeks or months to see any improvement

So, I am mainly overall better than the last time I posted. I do have bad days sometimes. I also feel I have post nasal drip in the morning. and I actually can see it on the back of the throat, but it doesn't seem to be much.

I don't know if LSN can cause real post nasal drip.

Thanks.

I hope this is useful for any of you.

Post Edited (albertocastillo2001) : 5/19/2016 9:28:58 AM (GMT-6)


albertocastillo2001
Regular Member


Date Joined Apr 2014
Total Posts : 53
   Posted Today 11:47 AM (GMT -6)   
I got ill a few weeks ago and it took sometime to get off the leftovers, however it wasn't that bad this time, althought I felt fullness and constriction on the side that I have problems with (chest and throat)

My doctor also recommended montelukast for allergy which I have been taking for more than 3 weeks and raising gabapentin to 900mg

I am unsure if I feel better, but I feel much better in the mornings.

However I still feel that annoyance, phlegm on the right side of throat and pressure in the right side of chest and throat, my voice has improved a bit

Last Friday and a laryngologist saw my throat. There's nothing there anymore, vocal folds move properly, piriform sinus are fine as well, arytenoids are perfect, no signs of any reflux or irritation, so has suggested that maybe my problems now are below the larynx.

Any help from you guys on what to check? I had neck CT scan with contrast which was clear and a chest CT Scan which is clear too

I still have that whistling sound when exhaling forcefully on my throat, but I think it got a bit less but can't be sure.

The gabapentin however did improve the throat clearing "attacks"

Any suggestion guys?

albertocastillo2001
Regular Member


Date Joined Apr 2014
Total Posts : 53
   Posted 7/23/2016 7:57 AM (GMT -6)   
Hello

A Killian Jamieson diverticulum as found on my cervical esophagus. Maybe this one is causing the left over symptoms I still have.. I am incredibly shocked because nobody found it earlier after all so many tests.. so now I feel really upset as now I have something else with me.

Chandra Tastet
New Member


Date Joined Jun 2018
Total Posts : 1
   Posted 6/13/2018 2:14 PM (GMT -6)   
Can you tell me how Amitriptyline caused a system shutdown ?

albertocastillo2001
Regular Member


Date Joined Apr 2014
Total Posts : 53
   Posted 6/13/2018 2:18 PM (GMT -6)   
Hi Chandra

Can't really say how it happened. Probably because I was too sensitive to it and began with 25mg

My next steps now are meeting a doctor for surgery to remove the diverticulum
New Topic Post Reply Printable Version
36 posts in this thread.
Viewing Page :
 1  2 
Forum Information
Currently it is Saturday, June 23, 2018 8:02 PM (GMT -6)
There are a total of 2,974,633 posts in 326,194 threads.
View Active Threads


Who's Online
This forum has 161293 registered members. Please welcome our newest member, Lymegone.
360 Guest(s), 4 Registered Member(s) are currently online.  Details
Confused2910, Dave62, enjoygolf, nepol