Elavil/Amitriptyline - anyone tried?

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Andy1986
Veteran Member


Date Joined Dec 2012
Total Posts : 1171
   Posted 6/12/2014 5:10 AM (GMT -6)   
Hi all

I have been suffering with on and off stomach problems for the last couple of years, and in the last couple of months I ate something that set my stomach off on one and it has never settled. I get burning in my stomach after eating or drinking anything although it is bearable when I stick to bland food pH 6 or over. If I have anything pH 5 or below it seems to burn. I also suffer from heartburn frequently. Max acid suppression obviously helps but just takes the pain from "kill me now" to "this sucks".

I was put on Elavil two weeks ago, very low dose of 10mg. My stomach does seem to have improved a bit, for example I could not lie flat before without getting stomach pain, but now I am able to lie flat with only mild discomfort. Also there are some meals where it doesn't burn afterwards! Does anyone know how long it takes to feel the full effects of it? Im cautiously optimistic that I've seen some improvement in the last 2 weeks, usually anti-D's take months and months to help depression but I heard its faster for pain relief?

I also take venlafaxine for anxiety and depression, last week I ran out for a few days a took none. My stomach felt better than it has in the last couple of months, but I suffered horrible withdrawl where I was exhausted and had insomnia. As soon as I started taking it again my stomach got worse but exhaustion and other symptoms went. Could this drug be making my stomach worse? I was put on it because I was told it had no stomach side effects, don't know whether it was just coincidence or not. Plus do I really need to be on two anti-depressants? Maybe it would be easier to wean off venlafaxine and just up the dose of amitriptylene if it helps.

mitnoy
New Member


Date Joined May 2014
Total Posts : 2
   Posted 6/13/2014 4:50 AM (GMT -6)   
Yes, I've taken Elavil. (Amitryptline) It is an anticholenergic medication that can help mask symptoms because it relaxes your GI system. You can use it for years if you don't have significant side effects. I believe it is actually a tricyclic antidepressant but it can be used off-label for this.

Whatever you do DO NOT have any kind of a fundoplication to control your reflux. The operation destroys lives routinely and most GI's will advise against it. If someone ever advises you to have one find the nearest door or window and run for it. That operation will destroy your antireflux barrier and,if the effects destroy your life or paralise your GI tract, they won't undo it. Beware.

Andy1986
Veteran Member


Date Joined Dec 2012
Total Posts : 1171
   Posted 6/13/2014 12:23 PM (GMT -6)   
Did you take it for GI symptoms or something else? If for GI how long before you felt its full effects?

I don't think anyone would operate on me even if I wanted them too, my LES is normal and I have esophagus motility issues, and with a sensitive stomach and esophagus I think it would be unbearable for me anyway. The only thing I've considered is the endostim, but dont worry Im not letting a surgeon anywhere near me in the this condition.
GERD, Anxiety, Depression, Rolling Hiatus Hernia, Esophageal Hypersensitivity

Andy1986
Veteran Member


Date Joined Dec 2012
Total Posts : 1171
   Posted 6/17/2014 3:37 AM (GMT -6)   
I saw the GI again yesterday and she said it takes about 4 weeks before it kicks in so hopefully Ill notice the difference in a couple of weeks time.

On the bad side my tests showed inflammation of my small intestine and my liver bloods are very abnormal, none of which would cause my stomach problems but just something else to worry about now!
GERD, Anxiety, Depression, Rolling Hiatus Hernia, Esophageal Hypersensitivity
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