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bdr1
Regular Member


Date Joined Aug 2005
Total Posts : 121
   Posted 8/26/2005 3:46 PM (GMT -6)   
Has anyone failed on other PPI's but succeded (symptom relief or healing) with Zegerid?
 
From what I've read and even heard from the rep in my office -- this drug is a re-branded Prilosec with Tums added ... at 10x the cost that it should be. 
 
So far, the manufacturer has no head-to-head data, so I'm wondering what experiences (if any) has anyone had?

CSNuts
New Member


Date Joined Aug 2005
Total Posts : 4
   Posted 9/22/2005 7:35 PM (GMT -6)   
I know this post is a little old but I thought I'd give you an aswer anyway... I have tried pretty much all the PPI's:

Nexium - Severe headaches
Aciphex - Very strange feeling in my head. Like it was going to explode without a headache?
Protonix - Sugar pills ;)
Prilosec - Not much help
Prevacid - Did great with the acid, pain and pressure but I started getting very strange chest pains after a little under a week.
Zegerid - Worked fairly well, after the 10 days of samples went to the Prevacid to try it out. Switching back this week after the Prevacid. We'll see in about a week how it's going the second time around.

Post Edited (CSNuts) : 9/24/2005 3:50:56 AM (GMT-6)


CSNuts
New Member


Date Joined Aug 2005
Total Posts : 4
   Posted 9/23/2005 6:20 PM (GMT -6)   

Okay, well the Zegarid will have to wait.  My copay would have been 246.00, 40mg x 2 a day.  Pharmacy suggests I talk to the doc about getting the 40mg generic omeprazole capsules instead.  I think I might try that since the GI was out of samples of the Zegarid and that's just a bit much for my wallet to handle right now :-) .

Here's a link to the back story behind the Zegarid formula that I found pretty interesting, http://www.southcoasttoday.com/topics/moneymattersfeb05/story8.htm.  It seems it was developed by a university pharmacologist trying to figure out how to get trauma patients with EG tubes the ability to take PPI's...

 

 


bdr1
Regular Member


Date Joined Aug 2005
Total Posts : 121
   Posted 9/25/2005 2:41 PM (GMT -6)   
Hey there CSN,

Wow! I would have never thought that a generic medication would have been so expensive!

If the Zegerid works for you --- you might be able to replicate some of the results for yourself. Zegerid (from my understading) works by immediately reducing gastric acid (via sodium bicarbonate) + a generic omeprazole. I would hypothesize that by taking an OTC medication like Maalox (calcium carbonate) with the omeprazole, you might be able to glean similar results. Again -- something that you'd definately have to discuss with your pharmacist. But, I don't see why it wouldn't work?

One very interesting point in the article that you posted was the fact that PPI's cannot be given through an IV. This is definately not the case -- as almost all of the branded PPI's have an IV formulation (Protonix, Nexium, Prilosec and Prevacid) ... weird that they wouldn't know this.

Hope that this helps!

best,
ckgMD

CSNuts
New Member


Date Joined Aug 2005
Total Posts : 4
   Posted 10/6/2005 7:03 PM (GMT -6)   
ckgMD said...
Hey there CSN,

Wow! I would have never thought that a generic medication would have been so expensive!

If the Zegerid works for you --- you might be able to replicate some of the results for yourself. Zegerid (from my understading) works by immediately reducing gastric acid (via sodium bicarbonate) + a generic omeprazole. I would hypothesize that by taking an OTC medication like Maalox (calcium carbonate) with the omeprazole, you might be able to glean similar results. Again -- something that you'd definately have to discuss with your pharmacist. But, I don't see why it wouldn't work?

One very interesting point in the article that you posted was the fact that PPI's cannot be given through an IV. This is definately not the case -- as almost all of the branded PPI's have an IV formulation (Protonix, Nexium, Prilosec and Prevacid) ... weird that they wouldn't know this.

Hope that this helps!

best,
ckgMD
Thanks for the tip ckgMD, I'll talk to the pharmacist.  Currently I am taking 4 Prilosec a day as my insurance balked at paying for even the generic omeprazole since it can be purchased over the counter.  Go figure!  They sent the GI's office a form to send back to the insurance company but we know how that goes...  Anyway, the Prilosec seems to be working okay, not as good as the Zegarid.  If I can accomplish the same thing for 1/3 of the money I'm willing to give it a try ;)
 
BTW, I dug a little deeper and it seems it's not that the PPI's don't come in an IV form it is that they work just as slowly.  At least that's what they say in this article, http://atmizzou.missouri.edu/jul04/Ulcers.htm
 
 
Cat
 

dkendall
New Member


Date Joined Oct 2005
Total Posts : 2
   Posted 10/7/2005 3:59 PM (GMT -6)   
I have been on Prevacid which has worked well for the most part.  Been on Prilosac which hasnt worked well,  have a bunch of samples of Zegarid and so far it has worked the best.   Havent checked in about the cost because I have plenty of samples for the time being, but will need to check on that.  Hope this helps.

friendlygal
Veteran Member


Date Joined Dec 2006
Total Posts : 722
   Posted 8/15/2007 12:20 PM (GMT -6)   
I know that this is 2 years past the time this post was written, but I'm glad to hear positive results from Zegerid. Because I've been suffering TERRIBLY and Zegerid is the only PPI I haven't tried yet.  I will ask the GI if I can give it a shot.  I want to have hope that SOMETHING will work!!

elcamino
Veteran Member


Date Joined Sep 2005
Total Posts : 1744
   Posted 8/15/2007 12:40 PM (GMT -6)   

Wow--I didn't realize zegerid was so expensive.  Fortunately, my insurance does pay for it.  Plus, for those of you who are taking it, you can download a coupon (either $20 or $30) from the zegerid website and redeem it with your pharmacist.  I ended up paying $23 for my prescription.

Elcamino


Current dx: Rheumatoid Arthritis
Suspected dx: UCTD/Early Lupus
Current Meds: Enbrel, Plaquenil, Aciphex, Ultracet, Zyrtec, Allavert-D, Zantac, Tylenol PM
Past Meds: Relafen, Vioxx, Mobic, Voltaren, Sulfasalazine, Entocort, Prednisone, Humira, Reglan


friendlygal
Veteran Member


Date Joined Dec 2006
Total Posts : 722
   Posted 8/15/2007 12:50 PM (GMT -6)   
elcamino, thanks for the coupon info.  someone posted that his/her GI doc said that zegerid was the same as taking zantac??  Does YOUR GI say that?  Because I don't think it is...I think that it is like taking zantac + a PPI, all in one...

VV
Veteran Member


Date Joined Jul 2005
Total Posts : 1849
   Posted 8/19/2007 7:51 AM (GMT -6)   
Glad I read this post, will check out this med. I am always taking Prolisec with tums or Maalox, so maybe I will get more positive results with this med. Hopefully my ins will cover it.


friendlygal
Veteran Member


Date Joined Dec 2006
Total Posts : 722
   Posted 8/19/2007 11:58 AM (GMT -6)   
i tried the Zegerid, it didn't work for me.  But I found out that I have such major motility issues with my esopaghus and colon. And that is why I have severe reflux that is completely untamable.  So the GIs can't help me.  I'm sad.

melnms
New Member


Date Joined Oct 2007
Total Posts : 1
   Posted 10/23/2007 1:31 AM (GMT -6)   
Hey all. I was just reading on here about zegerid. My doc wrote it for me and it is very expensive. My insurance wouldn't cover it so I went to the p harmacy and asked about buying sodium bicarbonate pills..You can get them from the pharmacist without a prescription for around a dollar for 60. zegerid is 40 mg of prilosec and 1125 mg of sodium bicarbonate. I got my stomach dr. to write me prilosec and I take 2 of those and then the sodium bicarbonate along with it...the pharmacist said it works just the same at about a 200 dollar savings....The drug companies are crzzzzzy....just thought i would share with you guys....

TammyGrl0528
Veteran Member


Date Joined Jun 2007
Total Posts : 1345
   Posted 10/23/2007 11:13 AM (GMT -6)   
Just wanted to welcome you to healingwell, melnms.

Feel free to post with questions or comments, and I see you are already comfortable looking at older posts for information, which is a great thing to do.

Again, welcome to the healingwell family. I hope you stay with us.
GERD Forum Moderator
 
Please contribute today to keep healingwell going!
 
Diagnosed with Generalized Anxiety Disorder (GAD) and Panic Attacks.
 
Almost completely healed from a battle with Agoraphobia!!!
 
Currently taking 20 mg of Lexapro at bedtime.
 
Clickable Link that may be of interest to some...as I find I often like to check drug interactions...Drug Interactions
 
Best Wishes to ALL...
 
~Tammy~


doghouse
Regular Member


Date Joined Oct 2007
Total Posts : 138
   Posted 10/23/2007 1:10 PM (GMT -6)   
I was on prevacid in the morning and given zegerid to take at night for two weeks when I got esphogeal spasms.  I didn't notice any difference when I took both medication. 

backpack
New Member


Date Joined Mar 2009
Total Posts : 1
   Posted 3/14/2009 10:21 AM (GMT -6)   
I am a 40 year old woman who has been suffering with stomach pain/spasms, acid reflux and so on for 20 years. My Father died at 62 with eosphogeal/stomach cancer. I am desperately trying to be proactive in maintaining my health through excercise, diet and regular doc. visits. However the symptoms persist and I am very frustrated. I too get severe chest pains. I always feel it coming on. It starts slowly and most of the time reaches a point where I can't even communicate or stand up straight for at least an hour. I feel it all the way up to my neck/throat and through my back. My new doc. thinks this may e eosophogeal spasms and has now put me on zegerid. I can't stand having to be on meds. regularly but if that is what I have to do I guess I'll deal but I am not confident with this diagnosis. I know my chest pain is not related to any meds. - it's a symptom of something that they just can't figure out. Has anyone had their gallbladder checked to make sure the symptoms they have are gallbladder related? Don't just stop at a regular ultrasound. Stones may not be the problem - it could be the functioning and then that would not show on a ultrasound. I'm going for a CCK-Hida scan soon. I've had an internal endoscopic ultrasound also which came back fine. My Father ad tests done that showed his gallbladder was fine and when they operated the surgeon found a severely diseased organ. If anyone has an input or helpful advice please let forward.
Thanks....

stkitt
Elite Member


Date Joined Apr 2007
Total Posts : 32602
   Posted 3/15/2009 10:34 AM (GMT -6)   
backpack
 
Welcome to HealingWell and the GERD/Heartburn Forum. Thank you for you introduction.  I do not have a gallbladder so I cannot comment much on that.  I do believe if a member is not confident in their physician it is always wise to get a second opinion or a third if that is what is necessary.
 
Again a warm welcome to HW>
 
Kitt
 

Kitt, Co-Moderator: Anxiety/Panic & Depression
&  Moderator GERD  Forums

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Peace does not dwell in outward things, but within the soul
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