Sertraline (Antidepressant) and GERD

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New Member

Date Joined Jul 2014
Total Posts : 12
   Posted 8/17/2014 3:27 AM (GMT -6)   
Hi guys, I've been suffering from bad GERD for about 2 years, recently however I was diagnosed with depression. I've been put on sertraline, which is an antidepressant. It's changed my life and I feel a lot better in my self. However, my GERD symptoms have gone down dramatically! I can lay down after eating and even drink coffee now. I was diagnosed with a lax oesophagus.

I've read that sertraline has a chronic pain numbing effect, which is something I'm worried about. I'm not sure if my GERD is actually getting better or if the antidepressant is masking the pain.

I have a hospital appointment soon to discuss surgery, but i'm stuck in this situation.

Has anyone had experience with this before, is it the antidepressants that are masking the pain? Or am I getting better?

I look forward to your reply.


Veteran Member

Date Joined Dec 2012
Total Posts : 1178
   Posted 8/17/2014 4:43 AM (GMT -6)   
Yes I'm on amitriptyline, an anti d also used for nerve pain and it's dramatically improved my pains. My heartburn is pretty much non existent now but still get stomach trouble.

I don't like taking pain killers or things to that effect normally as I see it as pain is there for a reason, but some people are overly sensitive and my endoscopy showed perfectly healthy esophagus and stomach despite pain so am pretty sure I'm hypersensitive.
GERD, Anxiety, Depression, Rolling Hiatus Hernia, Esophageal Hypersensitivity

Regular Member

Date Joined Apr 2012
Total Posts : 61
   Posted 8/17/2014 5:24 PM (GMT -6)   
Hi Andy,
Have you had any side effects from the elavil? I have some but haven't started yet. I have anxiety over taking meds....
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