PPI's and delayed gastric emptying

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CAGU
Regular Member


Date Joined Apr 2014
Total Posts : 315
   Posted 9/15/2014 3:39 PM (GMT -6)   
I developed delayed gastric emptying from taking a PPI (omeprazole 20 mg). It happened after I had only been on the medication for eleven days. I am positive I did not have this before I started taking the medication and omeprazole was the only medication I was on. I now had food and acid coming up to the back of my throat no matter what I ate and a constant sore throat, burping, excessive mucous, bloating, and globus sensation. Could not even eat a cracker without experiencing this. Also stomach pains after I eat.
Now for the good news.... If a medication caused the delayed gastric emptying, there is a good chance it will reverse itself. So, I quit taking the medication. Unfortunately , I had to get worse before I could get better due to "Acid Rebound" (anytime you quit taking a proton pump inhibitor after you've been on it for 2 weeks or longer you will go thru acid rebound. This happens since your stomach no longer knows how much acid to produce since you've blocked the acid for so long. It starts over-producing acid... They call this acid rebound)
Anyway, for the good news, once I made it through acid rebound, my delayed gastric emptying started reversing itself. it did not happen immediately. I have been off the medication for six months now and I am already 70% better. I am hoping by the end of the year, I will be at 100%. I realize I am very fortunate.
I knew it was important that I share this information. Even though not every one taking proton pump inhibitors will develop delayed gastric emptying, I still feel it is important to let people know that there is a risk this could happen.

Alcie
Veteran Member


Date Joined Oct 2009
Total Posts : 5028
   Posted 9/16/2014 8:19 AM (GMT -6)   
So sorry you had trouble with PPI. Can you take anything else to make yourself comfortable?

I hope you get better soon. Maybe your's is a case for surgery?

CAGU
Regular Member


Date Joined Apr 2014
Total Posts : 315
   Posted 9/19/2014 9:06 PM (GMT -6)   
Thanks Alice.. I am hoping I will not need surgery, since I seem to get better every month. For now I just chew gum immediately after I eat. It definitely reduces some of the acid reflux. Its not the chewing, but the constant swallowing when you have the gum in your mouth. If something is going down, it makes it harder for something to come up. So that is what I do until I am back to my normal self. Thanks for asking.

Loucath
Regular Member


Date Joined Jul 2014
Total Posts : 39
   Posted 9/20/2014 12:13 AM (GMT -6)   
Hi Cagu, how would you know if you had delayed gastric emptying?

Loucath
Regular Member


Date Joined Jul 2014
Total Posts : 39
   Posted 9/20/2014 12:21 AM (GMT -6)   
Cagu, just read the other post where you described delayed gastric emptying. Because I told my doctor I wasn't eating any bread as I felt it was just sitting in my stomach, she prescribed a motility drug called Domperidone which I am very reluctant to use because of the side effects. I have lost a lot of weight in the four months I have been on PPI's as they only have partially helped me. I get lump in the throat sensation and sour/bitter taste in my mouth and chew a lot of gum because of this. I don't think I have delayed gastric emptying though. I'm trying to eat more as I don't want to lose any more weight but it can be hard when you have these awful symptoms.

CAGU
Regular Member


Date Joined Apr 2014
Total Posts : 315
   Posted 9/20/2014 8:59 AM (GMT -6)   
Loucath,
I did not think mine was delayed gastric either at the time I was experiencing it. I lost 15 pounds. I had the lump in my throat sensation also. When you have delayed gastric emptying you stomach is not emptying properly, so you end up with more reflux than you would normally have (in severe cases you would have vomiting). Your body will make a lot of mucus in the throat area to try to protect your throat from the acid coming up.

CAGU
Regular Member


Date Joined Apr 2014
Total Posts : 315
   Posted 9/20/2014 9:01 AM (GMT -6)   
There is a simple test the can be done at your local hospital. The test is the delayed gastric emptying test. It is an out patient procedure.
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