sorry to hear that,
But you should really consult a doctor, but have you tried highter dosages of zantac and other ppi.
150mg zantac is quite a low dose.
you can certainly try different PPI, if nexium does not work then i doubt omperzole will work for you. You can try rabeprzole, pantoprzole, dexilant.
also in H2 blockers you can try famotidine, cimetidine and nizatidine. I would consult with a doctor for dosates and try see what works
If you are refluxing bad then maybe surgery might be option, but in the meantime really get the reflux under control because you can damage the esophagus seriously if its painful reflux.