My daughter did this with doxy - she took it at night with insufficient water and it hurt her a whole lot. My daughter caught it fast and drank a ton of water to wash the pill down. It took a day for her to feel better.
A friend also did this with doxy in the same way as my daughter and had an actual ulceration. It took a few days for her to recover IIRR.
52 yrs old, IBD diagnosis in spring '01. Proctitis, gastritis, ileitis.
Pentasa (3g/day) generic Colazal ( 9 6 pills/day), Sulfazine (1.5 g/day), Prevacid, folic acid, vit. D (2K iu), flax seed oil (2 tsp/day), psyllium (2 tsp daily), mesalamine enema as needed. Gluten free as of 5/30/11. Scope in 8/11 found no evidence of inflammation!