Proton Pump Inhibitors (PPIs) like the ones you mentioned are a tricky thing. Everyone's body is different so one PPI may work better for you than another. Unfortunately, doctors know this and sometimes will prescribe something different to see how your body responds to it.
The first PPI I was given was Nexium. And while Nexium was a great relief to a relative of mine who took it, it made me extremely dizzy and gave me awful migranes. So my doctor then switched me over to Prevacid.
Prevacid put me into the ER because it cause horrific abdominal pain. My GP doctor told me I had an "unusually sensitive body" to medications.
They say 3 times is a charm, well in this case it was true. The 3rd PPI that the doctor prescribed me was Dexilant. And that was the one that worked best for me because my body not only tolerated it pretty well, but it also alleviated my symptoms much better than the other two. Unfortunately, it was also the most expensive of the three and my health insurance only covered about
50% of the cost, so it was still about
$70 out of pocket for a 30 day supply.
But I happily shelled out the cashola for it because it worked so much better than the other two. PPIs are one of those medications that you have to try out and see how your body responds to them. For some people, like myself, you might have some side effects show up for a few days but then might go away too.
With the Dexilant I felt slightly dizzy and had some muscle tightening going on for a couple of days but then it subsided. So it took a couple of days for my body to get used to it.
When a doctor prescribes me medication now, I ask them WHY they are prescribing it over another drug. I have found doctor's answers to be very different from one to another. It's fascinating to me.