Posted 6/28/2020 2:06 PM (GMT -6)
My name is Ruby..I'm from india, Kerala..I'm 36 years now..I was diagnosed with a loose LES in 2007,ie, when I was 22-23 years..I didn't have any heartburn, no regurgitation..had just some sneezing sometimes, and a mild asthma only at night for which I used just a puff of asthalin inhaler ( I had allergy and mild asthma from childhood)..I had generalized anxiety disorder and developed panic attacks before University exams at my 17th year.. have been on a low dose of Venlafaxine( VENIZ XR) for almost 10 years..during this time I had only the above said negligible symptoms..later I tapered the drug in 2013 and stopped completely within 5 months ( bcs of withdrawal symptoms)..gradually I developed dyspepsia and food sensitivities ( which I didn't have while on the drug)..my asthma and rhinitis also increased..I cud not eat well..till that time I was not aware of the disease called GERD..one day I happened read about GERD and it's complications on the internet and was horrified..I had panic attacks..went to a psychiatrist ..have been prescribed Escitalopram and Amisulpride..I researched on Nissen surgery and fixed the date..before the surgery I stopped the medication and developed full fledged GERD with heartburn..the surgery did not fix it..i was surprised that I didn't have this for those 10-11 years with a loose LES..went again on Escitalopram with no relief...stopped the medication...2 years of suffering..
Recently I read a post here by a man/woman ( forgot the name) who got relief from a homeopath who dilated his pylorus and told his GERD is because of slow food emptying..it gave me some hope..I realised that most of my symptoms are because of the muscles of my stomach are not much relaxing(though my LES is lax) ( I cannot eat much..food is not getting digested well and emptied..as a result acid is remaining in the stomach)..
I became sure of this as my GERD worsened some days before , during and some days after menstruation ( the time at which muscle contraction happens)..Domperidone or motilium can fix this type of gerd to an extent but in India it is available only as a combination with ppis..without acid the activity of motilium will be limited ( I think)..besides, domperidone causes prolactin increase in blood and absence of menstruation, etc..
This horrible disease lowered my quality of life as my otherwise manageable anxiety peaked and I developed depression too..so I wanted a medicine that increases hunger and elevates my mood..I bought Veniz XR 37.5 (lowest) and had it just after breakfast..within 2 hours I will be hungry again and have food..within 5 days my heartburn was absent till 4 in the evening..then I had dinner at 6 in the evening and had 1 more veniz 37.5 just after dinner... within 5 more days my gerd diminished considerably..some setbacks were there..but as ill luck would have it I developed tachycardia on two times drug..so after some days I stopped the evening dose..still I don't have horrible gerd..I'm planning to visit the psychiatrist after the COVID and ask if there is any other drug which has the same effect without tachycardia..if not I will keep the morning dose and ask for any other low dose combination drug.. don't know whether it will work or not or how long it works...still some hope is there.
Sorry for the length and my poor English..wanted to let you know..if it helps anybody I will be happy.