I used to be on Protonix, until I went to a mandatory examination (forgot what it was called) where they ran a scope down my throat to check the esophagus, and the stomach area. They found ulcers and polyps up and down this area, all caused by GERD, and in spite of being on Protonix. My family doctor then switched me to Prevacid, and the episodes of reflux became almost non-existent. However, after some time I found an ingredient I didn't care for in Prevacid, as it was the similar ingredient in aspartame, which I didn't want to be taking. I have since been on Nexium, and have found that it works the best for me. My GERD 95% of the time occurs when I lay down for sleep. The few times I may have to deal with it now are if I've eaten chocolate too close to bed time, or caffeine or too large of quantities of food close to bed time.
Oh, while on Prevacid I wanted to see if I could quit taking it. Wow. Within two days my stomach was churning out more acid than I think it ever had before, to the point that I hurt. I went back on it. I won't quit again until my weight gets down where it belongs, and then I will have the doctor bring me some counsel on how to do it.
One more point, excessive weight is definitley a negative against someone struggling with GERD. The extra weight puts pressure on areas of the esophogus that allow the stomach acids to proceed higher than they should, and then the next thing you know you are breathing in that good old stomach acid. Man, there is nothing worse than that.
Anyway, I hope something I have shared helps, and that you find great success.
May the Lord grant you Peace!