I have been on nexium for 1.5 years right now (I'm 23 years old). I brought LPRD on myself by binge drinking one night.
Reading the research that Nexium might cause stomach cancer is disturbing, but, I have tried multiple times to taper off and to cure this by diet and have been unsuccessful. I even went on the Paleolithic (caveman) diet (strictly lean meats, natural foods, veggies, etc) which is all GERD-Friendly foods, and I still felt the acid. I have not had luck eating DGL before every meal, I never seem to have it with me or remember to. And even when I do, I still feel and taste the acid creeping up my esophagus and throat when I sleep.
Even so, the way I look at it is, if you DON'T take the nexium, you will be exposing your esophagus to refluxed acid for the rest of your life, which will more than likely cause cancer or barretts eventually.
In my judgement, its more dangerous to not take the drug than to take it. I think ultimately a surgical solution will be the solution for our problem. I'm not so sure how successful the nissen wrap is, but I actually read about some interesting alternative surgeries (http://real-efcl.net/heartburn/newprocs.htm) but haven't heard of any follow-up to them.