I have also noticed an increase in throat issues after eating a DGL lozenge.
On another note. When people say PPIs "don't work for me" I think they need to be more specific, and more specificity is needed to recommend an alternate treatment. If a person still has heartburn after taking a PPI, they might need to take it for longer and give the esophagus time to heal. If a person has continued regurgitation (stomach fluids coming up, reaching mouth), then all PPIs are doing is making the reflux less acidic but the person will still have problems.
Recommending Betaine HCL for people who have a regurgitation problem will not help, it will make things worse if anything. My 2 cents.