In reply to knight: I am glad the PPI's are working for you. Unfortunately, for some of us they don't, especially if there is a mechanical problem which is the case with me. I have a small sliding hiatal hernia and yesterday, I spoke to the nurse practioner and she said there was a problem with my LES (something about the pressure was off), I had the esophageal manometry test. This was her observation and the gastro doctor was going to intrepret the test today and would call me on Monday because of his tight schedule. But, definately she said there was a problem. I have taken tons of PPI's in fact, right now I am on Prevacid 30mg twice a day and at night I supplement with Zantac 300 and still I am on fire and the chest pain is unbelievable and I am on the strict gerd diet. Also, when they took out my gallbladder 3 plus weeks ago I also had an endoscopy and the surgeon said my esophagus was very inflammed and what has probably saved it some is the high dose of PPI's I have been on for so long.
As far as the PPI's goes, you can do research on the internet regarding bone-loss and the use of PPI's. Of course, this is more prevalent when you have been on the PPI's for years. As far as myself goes, I have the proof that this is actually the case. My doctor said that my osteopenia had gotten worse and it had spread to my hips (but don't forget I have been on double doses for almost one year). I am pretty darn sure when I get the bone density in Dec 07 it will more than likely be worse. I am not trying to scare you but I know this is the truth in my case. Also, many people who are on these PPI's for years can also develop anemia such as vitamin b-12 deficiency and of course the bone loss (more prone to bone fractures). No matter what, in order to absorb calcium, minerals you need stomach acid. Please do the research on this and you will be surprised at what you will find.
Yes, gerd can be very frustrating and causes a myriad of symptoms and it can totally change your life. I am so glad we have the gerd board where we can share information and get the support this dreaded disease causes.