I'm 2 weeks past my second shot....no improvement. a 5 day Prednisone taper ALWAYS cures my psoriasis for a few months before it comes back. I really want to try doing a 5 day prednisone taper while on stelara to see if that may kick start it. My dermatologist is 100% against using predisone for anything but my pcp may let me try it. Stinks that the one thing that helps me, prednisone, is so bad for you but it certainly takes care of my psorasis!!!