I started having chronic hives with bouts of angioedema at the end of Feb. this year. It has been about the worst six months of my life trying to figure out what is causing the hives and swelling. I've been on seriously every antihistamine available in combination with H2 blockers and Prednisone with absolutely nothing helping but the Prednisone. However now I am having too many side effects from the steroids! UUGGGGGGGGHHHHHHHHH!!!!!!!!!!! I have had testing for Lupus, RA, Mono, all being neg. Also IgE was neg and c4 and c3 were within normal limits. My TSH level was 9.5 and thyroid antibodies 37 so my Synthroid was increased. At that time my allergist thought all the symptoms were stemming from the thyroid imbalance, I thought.....FINALLY!!! But as my TSH level returned to normal and after my long drawn out Prednisone taper was complete....back came my hives! They almost seemed worse than ever, covering every inch of my body and they seemed to be "deeper" under the skin if that makes sence to anyone. My facial swelling (lips eyes chin cheeks) also began to appear more frequently and with it I get a severe sore throat and hoarseness in my voice. When this occurs I end up in the ER getting injections of Solu-medrol and epi. I kept a food diary for a month. My allergist told me that is most likely not a food allergy, or an environmental allergy because of the frequency of my symptoms and after keeping the diary nothing linked with the intensity of my symptoms.
I have run out of ideas, and quite frankly am ready to say _ _ _ _ it!! CU has consumed my life in every way making it impossible to function at work or take care of my family. I feel like such a burden on my husband and kids, and just don't know where to turn next. I know that 90% of CU is idiopathic, but I just can't help but think this is my bodies way of telling me that "something is wrong"!! I see my allergist on Wed. Not sure what the next step will be....still haven't had scratch testing because I can't get off the antihistamines and steroids long enough for accurate results!!! OMG!!! What a catch 22!!
OKay...I will shut up now! Just a relief to be able to let all this out to someone who knows what I am talking about!
Does anyone have similar symptoms/labs or any ideas? I am open to anything!!
Thanks for listening,
GERD, depression, anxiety, hypothyroidism