I have been using xopenex in my nebulizer since 2004. I was switched from albuterol to xopenex in the hospital because the albuterol raised my blood pressure and increased my heart rate. Thats the only difference I have ever seen between the two drugs. My regular asthma doctor likes albuterol better but the pulmonologist likes xopenex so I use xopenex and atrovent in a nebulizer twice a day and an albuterol inhaler in between.
I have had jitters for high dose albuterol, but most people don't require the level of medicine that I do.