Severe Urticaria (Hives) that don't respond to antihistamines & steroids

New Topic Post Reply Printable Version
40 posts in this thread.
Viewing Page :
 1  2 
[ << Previous Thread | Next Thread >> ]

New Member

Date Joined Jun 2009
Total Posts : 1
   Posted 6/20/2009 2:20 PM (GMT -6)   
A little over three weeks ago, my wife had a bad breakout of hives that started just as she was finishing a prescription (10 days worth) of Amoxicillin. She stopped the Amoxicillin that day and figured that she was having an allergic reaction to the medication. The hives continued for a few days so she visited her PCP. He gave her a prescription for prednisone and told her to take Clariton each day. Unfortunately, the hives didn't improve and a couple of days later they were so bad, and her face was so swollen, she had to take a trip to the ER. The doctors immediately gave her an IV and had to give her an adrenaline shot because her face and throat were so swollen. They also continued to give her prednisone along with allegra, benadryl, and pepcid. They assumed she had an allergic reaction to the amoxicillin and it was no longer in her system. It had been more than a week off the amoxicillin before she even entered the hospital.
After a couple of days in the hospital, the hives and swelling went completely away. She was dismissed from the hospital about 11:30am. At home that evening about 9-10 hours later, the hives started to return and all the medication (prednisone, allegra, benadryl, and pepcid) she was continuing to take, didn't stop the hives. She visited with her PCP earlier this week for a allergist refferal (darn HMO) and put her on Atarax instead of the Benardryl for the meantime. Again, no change. Hives were just as bad as ever, if not worse.
It has been over a week since her hospital stay and she has had severe hives (no dema though) every single day. They start around 8-9pm and continue to worsen through the night. they begin to fade through the day and begin new patches at night. Antihistamines and the steroids don't seem to be helping at all. They are actually just making her feel really terrible.  
Obviously, our next step is to get to the allergist. I just wanted to see if anyone else has had something like this or know someone who has had such a bad case of urticaria that steroids and antihistamines didn't help. Also, why did she clear completely up at the hospital when she is taking the same drugs now? Would it have been the IVs? Would it be because she was removed from the allergen? Does this sound more like a disease (thyroid, autoimmune, etc) than an actual allergy?
I have read at least a 100 websites on Urticaria and I am still just left really confused and frustrated. I love my wife and I am going crazy seeing her go through this.
Any help would be greatly appreciated.

Forum Moderator

Date Joined Nov 2003
Total Posts : 7160
   Posted 6/21/2009 3:40 PM (GMT -6)   
You didn't mention where on her body your wife is developing uticaria. That is often a clue as to the cause. Going to an allergist is really the necessary step in the diagnosis process. I suddenly developed an allergy to an unknown substance this winter. I didn't develop a rash but had severe breathing difficulties. My allergist ordered the necessary testing and got me on a course of medications that has finally gotten the problem under control. It took three months to find a medication regime that kept the problem at bay. It sounds like your wife has not yet had that right combo.
It is also possible that a cause of your wife's uticaria may never be found. There is an article that is quite good at explaining CIU [chronic idiopathic uticaria]. In the first paragraph of page 2, the article refers to "Table 1". Table 1 shows likely causes of uticaria based on where the wheals are located. This might help since you know where she is developing wheals.
Let us know what the allergist has to say.
Moderator Crohn's Disease  & Osteoarthritis Forums
CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, asthma, severe allergy and a host of other medical problems.

Veteran Member

Date Joined Dec 2008
Total Posts : 2386
   Posted 6/24/2009 7:49 PM (GMT -6)   
Strip down the house and sterilize it. Write everything she eats and drinks. See the allergist. Get PCP to prescribe EPI-PEN...if her face and throat swells again jab that into her thigh, rush her to a doctor/er.
Smurfy Shadow/Desirèe 
DX: Wegener's Disease, Migraines, Diabetese Type II, PCOS, Lactose Intolerant, Benign Heart Murmer, Depression, Asthma, Asperger's Syndrome, Necrotizing Gramultous Inflamation in eye, A.D.D., Acid Reflux, Tumor Behind the Eye, Carpal Tunnel, Fibromyolgia, Clasterphobic, Arthritis
Medications:  Tri Nessa, Percocet, Metformin, Prilosec, Protonix, Zantac, Advair, Cingulair, Albuterol, Calcium + Vitamin D, Pro-Air, Pepcid, Rolaids, Zofran, Compuzeen, Refresh Plus Eye Drops  PRN: Epi-Pen, Albuterol Nebulizer, Benedryl
Undergoing Radiation Taking Lorazepam (Ativan) on Radiation Days

New Member

Date Joined Jul 2009
Total Posts : 2
   Posted 7/15/2009 11:42 PM (GMT -6)   
Writing to let you know about my frustrating experience with urticaria, in case it helps. I am a 28 year old female and I woke up last December with some welts on my back and experienced swelling in my joints and severe pain in my muscles along with mild to moderate urticaria for about a month. After taking a strong antibiotic thinking it might be lyme disease, I had severe urticaria and had to go on allegra, zyrtec, and ultimately prednisone to get it under control. These medicines did work, primarily the steroid, but you cannot stay on steroids because they cause lots of other problems. The urticaria turned into Delayed Pressure Urticaria for a while, which while very annoying, was manageable. I was/am no longer able to lift weights, run, etc. because anything that causes pressure on my skin, including a heavy purse, will cause terrible hives within hours. It has always been worse in the evening and better by morning--other than the hives that are caused by the pressure points of lying down.

I have been tested for a million things under the sun, and they ruled out lupus, cancer, hepatitis, and a bunch of other suspects. I have also been tested a few times for my thyroid which was normal although I am still suspicious on that because I have read hives can precede a thyroid problem by months and even years.

I'm not sure if it was a result of the high level of histamine or a possible cause, but by May I developed a strong sensitivity to many foods--making me wonder if this was a food allergy. I realized I had a problem with all of the GERD problem foods--citrus, tomato sauce, carbonated beverages,etc. I also developed painful strictures in my intestines that came and went intermittently. I went on a PPI (Proton Pump Inhibitor) for 15 days to help with this, and the hives stopped. Unfortunately, shortly after I stopped the PPI, I developed chronic hives all over my body all the time--still worse in the evening.

Why on earth did the hives stop when I controlled my stomach acid? I continued searching other avenues, not able to explain this, and was tested for airborne allergens, which were mild and definitely normal (Note: I never had many allergies growing up and never had a sensitive system like this. In fact I had never had hives in my life). I also started to read about Leaky Gut, particularly on the Environmental Illness website, and although most traditional health practitioners don't subscribe to this--everything it says makes sense. Essentially, that a breakdown in the gut wall/weakness, either from food allergen, antibiotics, or something else like h.pylori, you stop filtering things as well and more junk from our food gets into our body and bloodstream, settling in joints and raising histamine levels. (Also why rheumatoid arthritis is tied to diet)

I started taking L-Glutamine because it has been mentioned on various credible sites for it's power to heal the intestines, as well as pro-biotics, and omega 3's. I'm also taking daily Pepcid and claritin. Last week, for the first time in over six months, the hives began to subside. I am hopeful that this regimen, along with avoiding gluten and eggs, and drinking lots of water, will ultimately stop the hives.

No medical practitioner has thus far been able to help me in any way. I have been to derm, allergy/immun and endocrinology, and as mentioned, undergone many tests. I have yet to see a gastrointerologist, but plan on it soon. I wish your wife a speedier recovery than me and I understand her and your pain--I would never wish this on my worst enemy. The reason this illness is so awful is primarily because you can never stop thinking about it with the constant itching. I will update this site as I learn more.

New Member

Date Joined Jul 2009
Total Posts : 2
   Posted 7/15/2009 11:48 PM (GMT -6)   
One further note, I have also had angioedema and swelling of my throat and tongue in conjunction with the urticaria--be sure to keep an epi-pen on hand in case your wife has anaphylaxis.

Elite Member

Date Joined Jul 2009
Total Posts : 14475
   Posted 7/16/2009 8:19 PM (GMT -6)   
I had an allergic reaction to Augmentin back in December. I had itchy hands on Friday night, Saturday they were 3 times worst, Sunday Night my top lip started swelling. All this time I was popping benadryl. Sunday Night I went to sleep with a slightly swollen top lip and woke up at three AM with severe facial edma. I looked like Anjeleno Jolene and Mic Jager all rolled into one. I was rushed to the ER barely able to speak due to my tongue starting to swell. I was there for two hours receiving IVs and shots. For almost a week I was in and out of the doctors office trying to get something to stop my hands from itching. I also had a strange, VERY itchy, red spotted rash all over my body. Finally a wonderful PA gave me something called Visterel (?). She said any stronger and it would need to be IV. I was on it for three weeks before I had total relief. If I was late taking it the rash came back with a vengence. She said it would take time for all the Augmentin to get out of my system. Maybe that's what's going on with your wife?

New Member

Date Joined Sep 2009
Total Posts : 1
   Posted 9/1/2009 12:47 PM (GMT -6)   
I have had some similar issues, and wanted to post my story to see if anyone else has had symptoms like i have, and if they got any answers, or maybe itll fit someone elses symptoms and at least let um know they aint alone.

This started back in early to mid june.

I have a chronic pain disorder due to a past surgery (Nerves all all messed up in my leg now) And i had just started taking a new pain medication, Lortab 7.5, 2 in the morn and 2 at night. No big deal, now generally with pain medicine i take it for 2 weeks and then off for a week or two and repeat in order to fend off any dependency that may be developing (Use to have a drug problem, and i don't want to go down that road again). Now the first month i took it, i took it for a solid month to let it build up in my system, so when i started to alternate, the weeks off the pain meds would not be horrific. Well as soon as i stopped the lortab, the next day i wasn't feeling too hot, and started to get bumps on my face and back that itched, i had never had hives before, so i had no clue what they where and simply ignored them and tried to stay out of the heat, cause i figured it was just a heat rash, the second day off the medicine, they got really bad all on my back and under my hair. It got me worried enough to goto the hospital, they gave me benedryl, prednisone, zrytec, and some other stomach medicine to no avail, and finally resorted to a Epinephrine shot, which did the trick and made me feel like i was going to have a heart attack haha, at least the nurse warned me so i didn't freak. Got out, and was given prednisone to take for the next 3 days, did this and took zrytec and i thought i just had a food allergy and that's what the hospital labeled it. The day i stopped the prednisone, the hives returned with a vengeance, the first time my face swole up extremely bad to the point my upper lip was touching my nose, this time thought they where on the back of my neck and going down my back and on my thighs, i started having problems swallowing and struggled to get air in and returned to the hospital, they did the same thing, except gave me prednisone, tagamet, and cyprohiptadine to take at home when the occurred again, this has gone on and on and on, except when im taking my lortab i have hives, but literally its only like 3 or 4 hives in a small area and that's it, as soon as i come off of it, the first day im off of it, it hits me hard, i take my medicine, pass out from drowsiness, and by morning they are fine, and then every day to every 2 or 3 days they return and i repeat the same things. I went to my PCP about them, he did a food test, and a test to look for Auto-Immune disorders, both came back totally fine in every way, the only thing that seemed odd was my Liver Enzyme levels where double normal, which is probably from all the heavy drug use i did back in the day and the life long use of pain medicine due to my leg. I have started to see a great allergy specialist/immunologist and he did some special blood test and told me to come back when i had hives, to get them re-done, same day i went for my original blood test i got hives and returned, he said my hives looked very odd, because instead of in patches i had some single little red hives all over my body, along with patches of hives. He gave me Xyzal and Claratin and told me it was obvious to him that the anit-histamine was doing nothing for them, in fact they where simply still progressing and becoming more defined, i still have not gotten my blood results, that's tomorrow, but im still courious if im alone in this issue or if others have had the same problems, my allergy specialist is worried it is Vasculitus and said he would know more once he saw my test results. Also i have in the past 3 weeks woken with my wrist and fingers locked up, taking hours to work them out enough to start my welding (I'm currently in college for welding technology). Also the other night my right foot swole up while sitting down, and after i got up and walked around it returned to normal, this is happened 3 or 4 times now, and if i take my neurontin it makes suppperrr bad, it makes me have burning pain in my shoulders and chest and throat, and hives extremely bad, obviously i discontinued use of the medicine.

Sorry for the massive wall of text, but maybe i can get a answer or at least feel like maybe im not alone in this, its aggravating and tormenting. Best of luck to all of you having issues, i understand very well it can be a emotional and financial strain when things arnt going well with your health.

Nana Monster
Veteran Member

Date Joined Jul 2009
Total Posts : 968
   Posted 9/1/2009 5:04 PM (GMT -6)   
Hi Peak,
   Check out stinging nettles. I had some bad hives and this helped. Also, if you need a steroid, yucca root   is
a natural one.
         Nana Monster

Still Hopeful
New Member

Date Joined Sep 2009
Total Posts : 1
   Posted 9/1/2009 6:47 PM (GMT -6)   
I've been reading the various postings on uticaria and other hive related problems. No one seems able to find out what my problem is, but uticaria seems closest.

In 2006, I was teaching in London, and came down with what I thought was a bad case of dandruff. It itched like mad. I used all the horrible products to keep it under control, but it never went away.

Upon my return to the states, the itching and red spots slowly seemed to move to my skin. I was told by a dermatologist that it was psoriasis (because of the head problems) but that was absolutely wrong. She finally sent me to see an allergist who tested me broadly from environmental things to food to household objects, pets, etc. No allergies.

Meanwhile, with the dermatologist, the small spots, sometimes red, sometimes white, began to cover my arms, upper and lower, my back, my upper chest, and in lesser amounts the rest of my body. They itched like crazy, and I unconsciously scratched - I was very busy. Soon I was covered in scabs, and soon scars.

I was given allegra, hydorchorine something at night, then zyzal to replace allegra (after a fight with my insurance...). None were 100% effective. I had cutivate lotion for my body (a light steroid I believe) and a stronger steroid for my head (which I used on my body when I couldn't stand it anymore - it worked better). The steroids have made my skin so thin that I when I rub it to stop from scratching, it leaves tiny bloodblisters. I stopped using any lotions, creams, detergents, any products with perfume, etc. So I cleaned up all my household products and detergents which helped somewhat. I was miserable. Stress definitely made it worse. When I went to Belize this last summer for a month, I swam in salt water and got lots of sun everyday and it got so much better. I just put on the regular "clean" creams (CeraVe for me) and used the antihistamines, and it almost seemed to be gone! Being stressfree helped. But now at home I take salt water baths, and it helps somewhat as well. I am now back to "awful" again.

When I saw the allergist, he seemed to know a lot more, and immediately gave me prednisonce on a 9 day course. When I was taking 3 a day (for 3 days) it was relief at last! But after that, it all returned with a vengeance. After the allergy test gave us no info, he sent me back to a (different) dermatologist since it is probably systemic rather than from outside, so that is my next step. Meanwhile he has given me Doxepin cream and tablets to help the itching and the stress. We'll see how it works.

However, along the way, I did find a product that really helps the itching without heavy drugs (most of the time...). It is called "Derm Essentials) and is for seborrheic dermatitis, but helps my condition too. It is nothing but essential oils and smells wonderful too. You can find it on the internet under that name.

Thanks for listening.
Still hopefull (after almost 2 years!!)

New Member

Date Joined Oct 2010
Total Posts : 1
   Posted 10/8/2010 11:06 AM (GMT -6)   
My 7-yearold son is going through the exact same thing that your wife is, sounds like. He feels great, just has hives that seem to come and go and move around his body now for 2 weeks. He too was on the amox and pred RX. Did your wife ever figure anything out? Did they finally go away on their own? Thanks for any help!

Veteran Member

Date Joined Oct 2009
Total Posts : 5022
   Posted 10/8/2010 7:06 PM (GMT -6)   
I'm sure you have done plenty of reserching, but here's a website you may have missed about skin allergies.
I get allergic skin reactions if my laundry isn't double rinsed or I don't use All Free and Clear.  I was in the hospital for the last week and a half and all they did for my skin problem to start with was to give me Benadryl, which put me to sleep but didn't last long enough for the breakouts to go away.  I finally found out the do have double rinsed linens there, which helped immediately.

New Member

Date Joined Oct 2010
Total Posts : 1
   Posted 10/11/2010 12:50 AM (GMT -6)   
Peak and jayed105,

I am going through very similar thing. I have sever hives starting every night around 9 and they go away slowly during the day, only to start all over again at night. I went to the er this morning and they gave me some prednisone but I am worry that it is not going to be enough.

Please share your experience how you get it treated and whether you found out what caused it.

Thank you much!

New Member

Date Joined Nov 2010
Total Posts : 1
   Posted 11/12/2010 9:27 AM (GMT -6)   
I've had chronic uticaria for over 30 years -- finally found out accidentally that Prilosec and Allegra treat them for the day...they may come back but this is better than the strong doses of prednizone I have been over the years and you can continue the treatment without many side effects until they just go away for good.  Also this helps:  Cut out anything with vinegar in it -- and that's lots of additives -- salad dressing, marinades, Worcestershire Sauce, barbeque sauces, mustard.  Also cut out anything with tomato sauce -- pizzas, red past sauces, etc. -- basically anything with acetic acid.  Also, cutting out powdered additives like taco sauce helps.  It's all trial and error.  Unfortunately chocolate has never given me hives.  A baked potato seems safe, too.
My chronic utility uticaria will stay around 6-9 months and then just go away.  Two members of my family also have this and cutting out the acetic acid helps.  When I have hives I notice a strong acidic taste on the tip of my tongue.  Anyone else have this? 

New Member

Date Joined Jul 2010
Total Posts : 15
   Posted 11/21/2010 10:04 PM (GMT -6)   
May I ask what was the highest dose of prednisone you were given?
For some of my systemic allergic reactions I have to take a higher dose than most docs prescribe BUT only for two days (like a one-two punch) then I go off.

If I did not do it that way, I would not have gotten rid of the inflammation caused by fire ants and other insects.

New Member

Date Joined Jan 2011
Total Posts : 12
   Posted 6/16/2011 5:09 PM (GMT -6)   
I have suffered Chronic Urticaria and Odema all day every day for almost 3 years now. I have tried so many of the medications you're all taking but I have some GOOD NEWS which MAY help some of you.
Before I go on, I would like to offer my opinion that after 3 years of doing my own research on all these different sites, I realise that Chronic Urticaria is NOT a skin problem, it seems to be an auto-immune problem.  Therefore Dermatologists can not really help.  The best person to see is an Immunologist.  (Obviously this is only my own observation and I can say this too because the itch etc was not actually on my skin, I used to repeatedly say to my husband : "it's deeper than that, it's inside me!!".  If you feel the same, then please continue to read..

My immunologist wanted me to try CICLOSPORIN (an immune suppressant). He told me he has SUCCESSFULLY treated many people sufferring with Chronic Urticaria. 2 years ago I was reluctant to try it as I was worried about getting "hairy" lol. But I had suffered so much that I couldn't take it any more so I went to him in April and started taking it.

It is now June and I haven't had any rash/welts/swelling/itching/burning/pain etc for about 8 weeks !!!! :)

It is amazing and I am so happy and I want to tell everyone who is suffering :-)

I've spent night after night after night on the computer trying to find myself a cure over the past few years and now I don't have to. But I wanted to help others.

Please bear in mind that the Ciclosporin can take about 6 weeks to get into your system. My immunologist put me on a "reducing dose" of steroids while we changed my medicines, and I came off the steroids very slowly but it worked and without suffering. I'm going back to see him next week and can't wait for him to see how happy I am as the last time I saw him I was in tears and covered in blood and scabs and now it's all gone!!  Reading the side effects is naturally slightly worrying, but I suppose it depends on how much each individual person is suffering.  I personally could not put up with it any more so I was willing to try anything mad
Good luck to you all, I know how you feel xx

P.S. I haven't got hairy yet - the hairs on my arms are fair anyway, they do seem slightly fluffier but I think that's a small price to pay! Still don't know what actually caused this horrible problem in the first place, but right now ..... I don't even care any more I'm just happy to feel human again.

New Member

Date Joined Oct 2012
Total Posts : 1
   Posted 10/15/2012 11:54 PM (GMT -6)   

I know this is an old post, but I thought that if anyone else with this problem reads it, I may be of help. I have gone through what ‘peakdescribed twice in life. So called chronic severe hives, that were not responsive to antihistamine or cortisol. , Both times the hives occurred few days after I finished the amoxicillin. The first time I was having them for almost 4 months and doctors were swearing there was no link to the antibiotics, consequently I was diagnosed with idiopathic urticaria. The second time it took about 6 months. Second time I also had additional symptoms like fever, really bad bone aches, night sweats, skin covered in something that appeared like white dusty-powder and ear itch.  

The hives were not caused by the amoxicillin as a substance itself – which is why the delayed and extended reaction (and I also had not tested as allergic to it, neither my Ig antibodies were ever increased during the out-brakes ). If something we could say that I was ‘allergic’ to what the amoxicillin has a potential to do to the healthy digestive system – ‘bad’ yeast overgrowth. In both cases I was treated with Nilstat (Nystatin) by the allergist. It took few repeats. I also taken number of supplements, one important one that was recommended to me by a medical practitioner who was also a naturopath, it was called Intestamine by Bioceuticals (the component you are after is called Glutamine) and strong probiotics. Second time I needed more repeats of Nilstat and I also invested a bit more in supplements, and got something called SB Floaactive with a strain of friendly bacteria called Saccaromycea boulardii.

Some recommend the candida diet and so on, I have never done it. Saying that I eat whole foods and no processed sugars anyway. Realistically speaking there are many different types of yeast and it may be something else than candida that is overgrowing. There are also many types of candida.  I stayed away from caffeine and alcohol for the sake of probiotics tho.

A word of advice: go to an allergist who specializes in yeast infections as most general practitioners will misdiagnose it. With general allergists you can spend your life searching for that one ‘allergen’ and find out it’s environmental and it cannot be avoided anyway. It’s better to fix the immune system from being confused. Some people suffer with hives due to yeast overgrowth after use or abuse of penicillins for years as a result of that ongoing misdiagnosis.

Last time I was told the hives are an evidence that my immune system  is very resposnive and it will go away when my 'gut' gets fixed. Unfortunately this does not happen overnight.

Good luck.

New Member

Date Joined Nov 2012
Total Posts : 1
   Posted 11/10/2012 8:55 PM (GMT -6)   
Just curious, has anyone in this thread also had enlarged lymph nodes along with all the other symptoms? I have alerady been checked for lymphoma but curious if others suffering from chronic hives also have enlarged lymph nodes.

Regular Member

Date Joined Aug 2012
Total Posts : 27
   Posted 11/10/2012 9:19 PM (GMT -6)   
Grendel said...
Just curious, has anyone in this thread also had enlarged lymph nodes along with all the other symptoms? I have alerady been checked for lymphoma but curious if others suffering from chronic hives also have enlarged lymph nodes.
Hi Grendel, to get off the track a little, I have used Ice Gel for an incredibly itchy rash which did not respond to trmt other than Prednisolone. It acted immediately and the rash started to recede the next day and has now gone completely. This is after two years of mis/non diagnosis and various treatments that did not work. It stopped the itch straight away!

New Member

Date Joined Nov 2012
Total Posts : 4
   Posted 11/11/2012 12:30 PM (GMT -6)   
It's been nearly a year for me. I have done TONS of research on this and it appears that doctors can test for a few things, but often find no apparent cause for chronic hives. Then they give allergy meds or steroids, which only serve to cover up the symptoms and do further damage to the body over time. Anything lasting over a few weeks is NOT an allergy.

I have reduced my hives by doing parasite and candida cleanses. My research leads me to believe that hives are caused by an infection or chemical imbalance somewhere on the body. Candida overgrowth is particularly difficult to get rid of. Talk about a needle in a haystack though! Most success stories come from people who repeat detox steps (without overdoing it of course). This can take months, but the hives often disappear out of the blue.

The most common cause is an infection or toxin or microbe infestation in the digestive tract. Tooth infections, gluten sensitivities, and thyroid issues can also cause chronic hives.

New Member

Date Joined Nov 2012
Total Posts : 1
   Posted 11/22/2012 10:37 AM (GMT -6)   
I had the same thing several years ago and I have it again now. The first time I had it, I had hives on my legs every night around 8-9 p.m. They went away during the day and came back each night. I tried everything...changing soaps, detergents, diet, everything. Nothing helped. Eventually, I went to the doctor. My doctor told me that they were caused by stress. Apparently whenever I tried to rest at night my body was trying to release so much stress and tension that my system was overwhelmed causing the hives. He told me that the solution was to reduce the stress. He also put me on some prescription strength antihistamine (I don't recall the name). I started taking the meds everyday. I also took steps to eliminate the stress. I ended a 2 year relationship that was causing a lot of stress and I got a new job with a lot less stress. The hives eventually stopped. Now, I'm in the same boat again. I guess I will have to re-examine life and find ways to get rid of the stress. That's the solution.

New Member

Date Joined Apr 2013
Total Posts : 2
   Posted 4/13/2013 7:19 AM (GMT -6)   
I am 36 male, 5'10, physically good health (blood pressure 110/74, good cholesterol levels, good kidney and liver levels, etc, except my testosterone level is low at 245 ng/dl - potentially from vasectomy from what my research has showed) and high eosinophils level was a 6, which I looked up and shows that eosinophils test counts the number of eosinophils (a type of white blood cell) in blood. It is used to evaluate and manage allergic conditions such as Allergic eczema, Asthma, Disseminated eosinophilic collagen disease, HIV infection, Infection by Anisakis larva, Infection by larvae of Trichinella spiralis, Infection by Schistosoma, or Infection by Strongyloides.  So, great, more stuff to bring up to a doc who didn't bother to tell me about this number....Good thing I asked for a copy of my lab results...Anyways, moving forward!
My Medical History:
I was previously treated by an Allergist in Colorado (Dr. Lora Stewart from Allergy and Asthma Care). I was scratch tested and was allergic to just about everything (all weeds, trees, grass, soy, cat, mold etc) and I was treated for 3 years with injections of these allergens starting with 2 shots a week small doses and building to a higher dose where it capped off and stayed at that dose with 2 shots/month for 3 years.  I never ever had hives before this, only asthma, which was why I was getting the treatment, so my airway would not tighten up after exposure to allergies. So fast forward to now, .... hives.
My Diet: Normal diet, mostly eggs, chicken, fish, cooked veggies, 2 generous glasses of wine (half bottle to be exact), I have noticed wheezing if I have too much wine(sulfites most likely but never had hives from wine), protein powders (whey protein), turkey sandwiches, chips on occasion, Cheetos on occasion, chocolate, pancakes, coffee, etc... I eat mostly healthy but cheat every now and then.
about a year and a half ago, my blood test showed that my thyroid was on the low side of the normal range (Range: 1 = High and 5 = Low). Mine was 5.5.  The doc put me on Levothryroxine, and a my levels have been very good at 3.5 right in the middle with the 50mcg of Levothyroxine daily.  I never had any reactions to this med, and this is the only med I take.  (maybe the itching is a sign of thyroid issue?).  I stopped the Levothyroxine for a few days and no improvement, so I'm back on it.
I am very curious about the posting from "Peak" at the top of this thread posted in 2009.
Out of the blue about 3 weeks ago, I began itching a lot with zero signs of any skin rash. After two weeks of scratching, I began noticing small raised clusters of whitsh clearish bumps after scratching.  The itching started on wrists and arms and then to my fingers.  The itching is intense and I want to scratch all the time however I try not too which creates a lot of tense stress from trying to refrain from scratching. It happens mostly at night starting around 9pm but it occurs in the afternoon around 2-3pm too. 
I went to a Dr. Steven Reynolds in Long Beach Ca, and he said it is definitely urticarial (hives) most likely from something I am allergic to and it was not scabies or bed bugs otherwise my girlfriend would have .    Dr. Reynolds gave me shot of Atarax and hydroxine pills to control the itching....and a week later, no results, in fact the hives got worse and now have bumps everywhere of red patches. 
I went back to Dr. Reynolds and now I'm taking the prednisone for two weeks starting with 3 pills a days and tapering down.  I have taken the first set of 3 pills and no results.  I am super itchy still and it seems Benadryl and zyrtec help only a little.  both sides of my neck have started to itch really bad too, along with behind the knees, tops of the thighs, groin, shins, fore arms, belly, arm pits. 
The only thing I can point to that changed in my diet was that I had a few juicing drinks of raw veggies.  I had roughly 3-4 glasses total spread over a few weeks, like one glass on the weekend, another during the week, and then again the following weekend, so not in high quantity.  The veggies I had ground up in the Juicer was Cellery, Raddish, Carrot, Spinach, Kale, Ginger. 
After taking the Juices I felt perfectly fine.  It was shortly after the (a day or two) juicing, is when the itching began.  This is the only thing I can point to that changed in my diet. I did notice too that I have been experiencing the reflux lately shortly after I stopped juicing.  I took tums to control it, but it went away, and I am not experiencing it now.  I am wondering if there is something in the juice that is causing my hives.  Some forums have many people who reacted with hives from juicing and continue juicing/detox made the hives go away, but I am afraid even attempt that.
I have spent hours reading forum after forum reading all the mystery cases of these hives where docs continue to band aid the symptoms with prednisone.  I have started to take probiotic Acidophilus and hope it helps but its too early to tell.  I began eating yogurt too.  The Candida bacteria sounds like possible cause or some other gastrointestinal imbalance or yeast.  The one post with the immune blocker medicine as last resort sounds promising but sounds risky...but better than itching and tension stress all night all day every day and reading forums from 1am to 4am every day.
If anyone reads this post and has a real answer to what this may be AND a Solution please contact me ASAP.  You can reach me at (  I will post a update after the prednisone.

New Member

Date Joined Jul 2013
Total Posts : 1
   Posted 7/30/2013 1:01 PM (GMT -6)   
I started having the itchy hives in Aug. 2012. I believe it is due to stress. In Aug. 2012 we were on a weekend trip to the beach, it was hot, we were trying to coordinate meeting for lunch, we had our one month old grandson with us, who was not happy, I was stressed about my daughter who was worried about her son crying and being miserable. AT the same time, I am trying to make sure everyone is having a good time. Anyway, that evening after we got home from a very long 3 hour car ride, I noticed what looked like mosquito bites on my wrist. It kept getting worse up my arms then my chin, neck. I went to bed not thinking it was anything to worry about.
I wake up the next day and I have the same itchy, no new improvement. Then I started to ask my whole family if they had a rash and nobody did.
So by Wedndesday, so the fourth day, I finally go into the urgent care because the rash has spread, no relief from the itch. They give me prednisone, zyrtec and Benadryl regimen. All of that helped. So here we are almost a year later and I am still on the same treatment, minus the steroids. I only take the prednisone when my rash starts to get out of control. The reason I attribute my rash to stress is that in June I started breaking out again, despite taking my meds, due to some stressful, hostile situations we were dealing with our neighbors. They are horrible people, anyway, that's another topic. Due to that situation, I noticed my hives return gradually. Now my daughter is getting married on Aug. 3 and the stress of that also, I believe has caused my hives to be more intense. I have started taking the prednisone again as needed. I am hoping that by the time the wedding is over, my hives will go away as I will not have this stress regarding wedding preparations and entertaining family from out of town.  S
Since probably Sep 2012 to May 2013, my hives did not completely go away, I would get spot or two here and there, despite taking the zyrtec and Benadryl, every day. I was ok with that, as I too am on a journey to try to figure out why I really get these hives. I have had thyroid issues, still take my meds for that too, I even had my thyroid taken out in Feb due having cancer, but the amount they found was so tiny, that I opted for them to take it and I did the radioactive treatment pill. So going through that in feb-May of 2013, did not really cause me any stress.
What I am going through now, is similar to my symptoms I was suffering when I first started getting hives. it does get bad at night and also I wake up with hives all over my face, once I take my zyrtec they do go down, but the redness is visible where I had a hive. when it gets really bad, the prednisone helps within 4 hours. the other scary symptom and painful is when I feel it in my throat, the feeling I have is like when you swallow food that is too big or like when you get food stuck in your throat when you try to swallow too fast?? anyway, that feeling comes in waves, throughout the night. I have not really read that this happens to a lot of people. Good luck everyone finding some relief from the itch. thanks for reading.

New Member

Date Joined Aug 2013
Total Posts : 1
   Posted 8/9/2013 11:24 PM (GMT -6)   
I'm hypothyroid, and I suffer from urticaria. I suspect the former causes the latter. I flare up only when an aggravating factor is present. My best guess as to that factor is an ingredient or contaminant in soap or laundry detergent.

My hypothyroidism went undiagnosed for years because I registered as normal on the standard test, for TSH. One lesson I draw is that a person can be hypothyroid, and suffer from hypothyroid's symptoms, even when his/her doctor says there's nothing wrong.

I suggest that if you suffer from urticaria, you have your thyroid function checked. If your TSH reading is above 0.3 -- the minimum level considered normal -- try to persuade your doctor to prescribe thyroid medication. If you're already on thyroid medication, try to have your dosage increased.

I can't promise it'll work, but it may be worth trying.

Best of luck, to all of us on this thread.

New Member

Date Joined Aug 2013
Total Posts : 1
   Posted 8/11/2013 6:04 PM (GMT -6)   
Hello everyone,

I'd like to thank all of you for your insights on this forum. I would like to share my brief story with urticaria thus far.

about a month ago I acquired poison ivy, due to this being on my face I was given prednisone 12-day by my doctor. This worked great (aside from the crazy thoughts and bloating). about 9 days into prednisone (as it was weaning down) I started developing hives everywhere and the itching was incredible (I lost the battle with the scractching). Subsequently, I went to the doctor twice more because of the scratching, my dosage was increased to a whopping 60mg per day plus all anti-histamines known (yes h1 and h2, from benadryl to zyrtec, montelukast to ranitidine. Nothing helped get rid of the hives and I was miserable as well as a walking pharmacy.

I gave up on my doctors and turn to Dr. google and found this and other sites where I narrowed what was happening to me. As you may know, our bodies walk a very fine line and balance is the key. I surmised that the reason for my hives was caused due to the prednisone suppressing my immune system and wiping out good flora in my stomach, which sometimes leads to excessive histamine being release systemically (hence my hives). I quickly had my wife assist me in getting the things I needed to rebuild my good flora:

Step 1: 2 days of taking diluted bragg's organic apple cider vinegar exclusively (morning, afternoon, evening x 2 diluted teaspoon in a 8 ounce water or green tea cup).

Step 2: after 2 days of that I started only taking that mixture once a day and commenced the flora building: kefir from wegman's (or other chain that carries this), vitamin d-3 (5000 iu), and swanson's probiotic 66 billion colony forming units product (1 pill a day). I made sure not to take the kefir or swanson's pill within a couple of hours of taking the apple cider vinegar; the vinegar will .

Step 3: continue with step 3 for 30 days until the probiotics run out (30 pills, 30 days), but continue the other components for upkeep.

In conclusion, about 4 days in to this methodology (steps 1 + 2) I stopped getting hives!!! Since our bodies are different your mileage may vary. I was lucky enough to find the perfect mix for getting rid of my hives (which by the way were driving me crazy due to doctors not helping and their medications were only dealing with the symptoms and not addressing the root cause).

I would suggest this to anyone that starts developing urticaria out of the blue or has been taking anti-biotics, prednisone, or any other drugs that kill our natural good flora.

Thank you again and I hope that this can help some of you in your fight against the evil urticaria.

Best regards,

Dr. Rulo (not a medical doctor)

Post Edited (rulo) : 8/11/2013 5:07:02 PM (GMT-6)

New Member

Date Joined Aug 2013
Total Posts : 1
   Posted Yesterday 10:56 PM (GMT -6)   
Hello, when this happened to me for the last 35 years off and on. I had swollen eyes, lips, legs, arms feet, tongue etc. Two years ago I found that I was allergic to my own progesterone. Before I found out, when I was premenstrual they became so bad I was hospitalized. My tongue had swollen so large I had a hard time breathing. I've been on Lupron via my Gyn and I have been free of the problem. A last resort is having a complete hysterectomy. I'm not at that point but the medication has put me in menopause. Have your allergist test for hormone response to both progesterone and  estrogen.  You must work with your allergist and gynecologist for this issue.
Blessings from the creator and good luck.
New Topic Post Reply Printable Version
40 posts in this thread.
Viewing Page :
 1  2 
Forum Information
Currently it is Saturday, August 18, 2018 7:22 AM (GMT -6)
There are a total of 2,993,995 posts in 328,096 threads.
View Active Threads

Who's Online
This forum has 161256 registered members. Please welcome our newest member, Gianna.
260 Guest(s), 6 Registered Member(s) are currently online.  Details
therearemiracles, sandyfeet, cashlessclay, Sherrine, 18yearsandcounting, Steve n Dallas