Bee stings/ methotrexate

Mods -- this is a cross post from the crohns forum.

Anyone ever have a severe reaction to a bee sting while on methotrexate?  I've always had a mild reaction, swelling of the area, itching, etc. but on Saturday afternoon within 15 minutes I was breaking out with hive head to toe.  I ended up going to urgent care and was told to take benadryl (already took 3 with no effect). The mtx is the only  change in my meds since the last time I was stung, so I guess I'm trying to find some correlation between the two.  Just wondering if anyone else had similar issues.

Going to PCP to get a script for an EPI pen.

I haven't been stung yet (and I hope not to!) but I am on similar meds - 6mp and Remicade. However, my body tends to overreact to certain things now. So it's very possible that the MTX caused you to become more sensitive to these things.

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SHERRY
Moderator-Allergies/Asthma and Alzheimer's, Co-moderator-UC
Diagnosed Left sided UC in '92 - meds: 6mp, Colazal, Remicade and Bentyl*Unable to tolerate ALL mesalamines*, in '11 diagnosed with IBS, Diverticulosis, Fibromylagia..I also have Sacroiilitis, Scoliosis, Raynauds, OA, PA, Rosacea, Psoriasis, Dry Eye and allergies controlled by Zyrtec and Singular