Benadryl is one of the few medications that is usually pretty safe when taken, however in young children you must be careful to follow your Dr.'s advice on how often this should be given. I know how you feel re giving your little one these types of medications! Sometimes we have to look at the risks we take when we do not give them something to help combat their allergies. It seems as if we are between a rock and a hard place! I have two children, a son that is now 31 and a daughter that is 17. They have both (along with their Mom

) had problems their whole lives with allergies, since their births, including asthma. I can tell you, though, that they are both very healthy and have been on all the following med.'s at one time or another, except for the Singular as that is a new one that wasn't available when they were as young as your daughter. My son took allergy shots for many years and that seemed to help him, though after a few years off of them, the allergies returned. Wishing you and your little one all the best!