Eosinophilia and High IGE

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New Member

Date Joined Feb 2014
Total Posts : 13
   Posted 5/4/2014 8:40 PM (GMT -6)   
Hello Everyone,

I am in my 20's, normal weight, I exercise a lot and eat healthy balanced meals. I have had high eos levels for about a year and no one seems to know what causes it and how to treat it. My eos levels were 16% at first and now they're down to 10%. I also have a high level of IGE serum (255 iu/ml). I have been tested for parasites several times but the results came back negative. My doctor said this condition could be caused by allergies and put me on allergy medications, but I don't have any allergy related symptoms and the medications don't seem to do anything.

I do have elevated thyroid antibodies (TPO Ab and Thyroglobulin) and a history of hyperthyroidism, hypothyroidism and gastritis. Can these issues be related to Eosinophilia and IGE somehow?

I am a bit concerned since my doctor told me that high eos levels can cause other problems, such as blood clots. Does anyone here happen to know what could be causing my high eos and IGE levels? Thank you in advance.

Veteran Member

Date Joined Aug 2007
Total Posts : 4415
   Posted 5/6/2014 9:55 AM (GMT -6)   
Yes, the thyroid and gastritis may be related to the eosinophilia and/or high IgE.

Eosinophilic Gastrointestinal Disorders can cause elevated eosinophil counts in the blood, and also high IgE. See www.apfed.org for more info.

Thyroid disorders predispose to the development of allergies (IgE-driven).

Also, unfortunately, most parasite tests in the US are woefully inaccurate (i.e., very high false negative rate). The best test of parasitic involvement is to treat for parasites and see if symptoms and/or blood counts improve... Pinworms are one of the most common parasites (they're airborne, so very easy to catch).

Chronic Lyme, Bart., Gluten & Sulfite Sensitivity, Many Food/Inhalant/Medication/Chemical Allergies & Intolerances, Asthma, Gut dysmotility & non-specific inflammation, Lupus, Osteoporosis, etc.; G-Tube; TPN-dependent
Meds: Flagyl, Zofran, Acupuncture, etc.

New Member

Date Joined Feb 2014
Total Posts : 13
   Posted 5/6/2014 12:57 PM (GMT -6)   
Thank you so much for your informative response. I'm going to ask my doctor to treat me for pinworms and other parasites and see if it works.
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