Prednisone and Hives

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Regular Member

Date Joined Jun 2007
Total Posts : 124
   Posted 5/8/2014 5:38 PM (GMT -6)   
I have had chronic hives for 2 years now :( they have no idea why. I had all the testing done and everything was normal. I have been on hydroxyzine, doxepin, zantac, allegra, zrytec, and singulair. I could not tolerate the antihistamines that are sedating. at the time I started I had a 6 month old who didn't sleep through the night. so I couldn't do it. I was on prednisone off and on until the past year I have been taking it daily. when I stop the hives come back full force. I only take 5mg a day however a few weeks ago I did get hives when I missed a dose. and they were BAD - I then took more prednisone for about a week now im back to 5mg. but im really worried about taking the prednisone now. ive been tired a lot the past 6 months and this past week the fatigue has been horrible. today has been especially bad. I am also on an antidepressant so I don't know if this is from the decrease in the prednisone or from my antidepressant? but I can hardly stay awake - I am also very depressed. I feel like I have shortness of breath and I can barely function. I was wondering if anyone else has been on prednisone for a long period of time what your experiences were with it and going off it? thank you.

also my dr recommended I go to a rheumatologist next for my hives since the allergist and dermatologist couldn't help me. has anyone had any experiences with this too?

Veteran Member

Date Joined Oct 2009
Total Posts : 5028
   Posted 5/8/2014 8:32 PM (GMT -6)   
Welcome to the forum, Nomorepanic.

So sorry you are having this problem! There are some other people who have had symptoms like this. Hopefully some will be along with suggestions. I'm sorry I have no idea how to help.

You can also put some keywords in the search box at the top of the page. There are other threads that might help you.

Best wishes! I hope you will keep in touch.

New Member

Date Joined Dec 2013
Total Posts : 4
   Posted 5/17/2014 7:57 PM (GMT -6)   
I can tell you that I know your pain. I have had hives for almost 2 years now. Never before been allergic to a thing and suddenly I was breaking out all over. It has been the most excruciating, horrible experience while at the same time helping me mature and grow so much in many areas. But enough of that. :) Suffice it to say, this "diagnosis" affects so much more than just the physical.
Yeah, all my tests came back negative as well and none of the Drs I went to liked the idea of me being on Prednisone long-term (although initially that was the only thing that had any significant effect). Allergy shots weren't working, and I had to find something that would let me live a somewhat normal life.
After trying every diet, home remedy, and medication in the book, I gave up and went to an alternative doctor. Believe me, I'm not the type of person to do this, but when you've been sick with this for 2 years straight with no relief you're willing to try anything, right? That's what I figured anyways.
I wish I could say it gets easier. Unfortunately, there are nights that I wish God would take me home so I wouldn't have to suffer like this anymore. Anybody who thinks this is over-dramatic hasn't experienced the sleepless nights, endless itching, and horribly disfiguring swelling. However, I have hope. Definitely a weak and sometimes wavering hope, but hope nonetheless. My alternative doctor told me I have leaky gut syndrome and has been able to help some, and we are working towards a cure. Maybe unrealistic, but to be fair I have seen more improvement with him than anybody else. The healing process is bumpy with lots of setbacks even when I am doing everything right. The only thing that gets me through is the knowledge that God has a plan for me through all of this, and He cares.
Hope this helps. Don't give up!
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