You are not alone. I hope you find something that works.
For my allergic asthma: Been on xolair for over 2 years, alongside allergy shots to desensitize to dust, pollens, and mold. Neither xolair nor shots seems to help much for the mold allergies, according to allergist and pulmonologist. Nonetheless I keep taking them & experiment with different mixes of other meds, also taking daily an antihistamine, singular, and inhalers. Have also changed dosing & frequency of xolair injections - did once every two weeks, then once a month, now back to every 2 wks. I think there are just going to be exacerbations (for me due to environmental triggers), and I just need to deal with them. Next step is to add prednisone if I really can't get it managed by these other drugs.
Wishing you well!
55 yrs old. UC >12 yrs after proctitus. For flares failed prednisone, cortenemas (too little too late), mesalamines (hives, fever), 6mp (fever), Uceris (no effect). 12/13: remicade stopped severe flare! 6/14: i stopped remicade due to debilitating joint pains & weakness. Dx: Anti-TNF Induced Lupus; polyneuropathy; recovered w/prednisone (40mg then very slow taper ~ 4 months). Next UC meds?