Multiple drug allergies/serum sickness?

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Veteran Member

Date Joined Dec 2006
Total Posts : 1986
   Posted 11/19/2007 5:21 PM (GMT -6)   
Just wondering if anyone else has had problems with this? 
I'm usually in the Chron's or Ostomy forums, but have recently been having problems with drug allergies. 
It started with Remicade (Infliximab) which I had a delayed reaction to (serum sickness) but I couldn't get any of my doctors to believe me (GI or Rheumys).  I finally had to go see a specialist who was involved in the Remicade research, who was 4 hours away and very expensive, to get my answers. 
Now it looks like it's happening again with 6 mercaptopurine, the same exact symptoms and of course my doctor (GI) knows nothing about the drugs he prescribes and doesn't know what to do. Of course I'm going to stop taking the drug, see what happens, but 2 drugs now, not related, it's starting to scare me. 
I'm going to go to an allergist, but I'm not sure how much she'll be able to help me as I went to her before for my Remicade reaction and she just gave me pre-meds and said to keep taking it.  
Now my doctor (GI) wants to start me on Methotrexate which is a scary drug to begin with, but the possibility that I may have another reaction scares me to death.  I've decided I'm not going to start taking it until I get some answers.  I'm kind of scared though, my GI has me scared to death about my Crohn's disease, and all the surgeries I've had to have.  Wants me on a meaintenance medication no matter what. 
My reactions have been migrating joint pain, starting in the fingers, moving  to the wrists, elbows, ankles, knees, feet.  When I couldn't get any of my doctors to believe me about the reaction to the Remicade, it ended up being the most excruciating pain I'd ever been through, and even once I stoped the drug it took months to go away.
Anyway, I was just wondering if anyone else has been through this, has any pearls of wisdom or recommendations.
Thanks for listening.

Crohn's Disease   
Too many surgeries, ileostomy6MP for maintenance.

Post Edited (JudyK89) : 11/19/2007 3:23:46 PM (GMT-7)

Elite Member

Date Joined Apr 2004
Total Posts : 23551
   Posted 11/19/2007 5:54 PM (GMT -6)   
Hi Judy :) Just curious, have you tried posting this question on the Cd or Ostomy forums? The reason I ask is that many people that frequent this forum may not even know what Remi, 6mp or Methotrexate is. No pearls of wisdom from me, I'm sorry but hopefully someone will come along and help you :(
~Left sided Uc -'92 - Colazal (9 daily), 6mp (50-75mgs), Prilosec, Biotin, Forvia, Pro-Bio, Hydrocortisone enemas**Unable to tolerate Asacol, Rowasa or Canasa** 
~Allergies - Singulair, Astelin(got the script - just haven't tried it yet!)~
~Secondary Reynauds Syndrome - '04 - Norvasc~
~Fibromyalgia - '06~
@--->--Moderator for Allergies/Asthma and Co-moderator for UC--<---@


Veteran Member

Date Joined Dec 2006
Total Posts : 1986
   Posted 11/19/2007 6:18 PM (GMT -6)   
Yes, I just posted on the CD forum, was just hoping that someone on here knew something about multiple drug allergies. Does this mean I'm going to have reactions to a lot more drugs, etc.

Thanks for asking though..
Crohn's Disease   
Too many surgeries, ileostomy6MP for maintenance.

Regular Member

Date Joined Sep 2007
Total Posts : 97
   Posted 11/20/2007 8:46 AM (GMT -6)   
Judy: I can understand your problem drug allergies. I am one that cannot take prescription meds.. I am currently taking all natural remedies and have never felt better in my life. I go to a homepathic doctor and take herbal remedies, minerals and vitamin supplements. I also had a food allergy blood test and eliminated the foods I was allergic to and that also made a big difference.

Alternative treatment may not be for everyone, but it surely another option. With nautural treatments, you avoid all the side effects of prescription meds
successful with herbal, vitamins and minerals

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