It's interesting that you mention how the Prednisone helps with your knee pain. Back in the 90's when I was very, very active, I wore out my knees. I had surgery on both knees several times and still continued to have pain and just learned to live with it. A couple of years ago a long time friend of mine who is a nurse asked me if I knew why I no longer had the pain in my knees. Of course I did not. She told me it was the Prednisone, which of course made sense to me.