I used to, many years ago, take Zoloft for depression. If I remember rightly it caused some nausea for the first few days and made me fatigued - although that could have been the depression. Might be worth bearing in mind that I was taking it as a minor, so my side-effects experince may be slightly different.
Dx: Panic Disorder, Psychotic Depression, Rheumatoid Arthritis
Rx: Humira, Methotrexate, Plaquenil, Prednisolone, Codeine, Diclofenic Sodium, Folic Acid