How long does it take for Zoloft to work?

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New Member

Date Joined Dec 2009
Total Posts : 2
   Posted 12/7/2009 10:41 AM (GMT -7)   
Hi all!
Recently I've been diagnosed with GAD (my symptoms are: nervous stomach, heavy head and insomnia) My doctor prescribed me Zoloft and Xanax when needed. I've been taking zoloft 0.25mg for 10 days, 0.5mg for a week and 0.75 for three days. I know everyone is different but how long does usually takes to feel some relief? I've never had this before and I am very new to this anxiety thing.

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 12/7/2009 11:06 AM (GMT -7)   
My daughter said she was feeling better after a few weeks on Zoloft. But for some folks it can take up to 4-6 weeks to fully kick in. Hang in there, better days are ahead.

Gail*Nanners* Co-Moderator for Crohns Disease & Anxiety/Panic
Crohn's Disease for over 34 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, Calcium, Vit D, and Xanax prn. Resections in 2002 & 2005. Also diagnosed w/ Fibromyalgia, Osteoarthritis, & Anxiety. Currently my Crohns is in remission, but my joints are going crazy!
*Every tomorrow has two handles.  We can take hold of it by the handle of anxiety, or by the handle of faith"*

Regular Member

Date Joined Feb 2009
Total Posts : 175
   Posted 12/7/2009 1:36 PM (GMT -7)   
Like Nanners said, give it 4-6 weeks. If you're having a hard time getting through talk to your doc about getting something to get you over the hump, it takes time for your body to balance out with anything. When I went on zoloft years back I had a script for Ativan to help me through. Just give it some time to work. Good luck and hang in there!

New Member

Date Joined Dec 2009
Total Posts : 2
   Posted 12/7/2009 1:38 PM (GMT -7)   
Yes, I am taking Xanax when needed. I supposed to go up to 100mg next week but I was just wondering when should I see the improvements. If I don't see it at 100mg should I change meds?

Forum Moderator

Date Joined Apr 2007
Total Posts : 32602
   Posted 12/7/2009 4:13 PM (GMT -7)   
I would give it the 4-6 weeks at the targeted dose your physician has set for you. It take time for these meds to reach their peak.

Good Luck,

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