What situations are you in when you feel like you need to take your medicine even more? On the weekends, I notice that I don't need to take my klonopin unless I need to go somewhere. But when I am at work, I definitely have noticed a need to take it more often. Sometimes even when I do take a half of a .5mg pill, it most always works. However, sometimes my panic is so overwhelming, it doesn't work at all. In fact, one day I had a doctor appointment, I took half a pill and my blood pressure and heart rate were high when I saw the nurse. It didn't even work for me! My doctor did tell me that my dose is so small, which is why it probably didn't work as well for me. Most people take the entire pill, but like I said, usually 1/4 tab even helps calm me. I guess it just depends on the panic attack and where I am at.