I have Pure O (no compulsions) OCD.
I had a great run on Prozac for 17 years before it gave out. "Prozac Poop Out". Most of that time I was only on 20 mgs. Sometimes up to 40. It was GREAT. Went months with near ZERO symptoms.
In September I switched to Lexapro after going up to 80 mgs of Prozac. Neither have done the trick. In fact 60 and 80 mgs of Prozac made my anxiety much worse. Then 20 mgs of Lexapro just increased the agitation and resulting Obsessions.
At the moment I am tapering off Lexapro. 10 mgs. for a couple of weeks then my Pdoc will switch to another SSRI. We both agree lower doses go a long way with me. That, even though it usually takes higher doses to be effective for OCD.
I have done a lot of web based research. I am very aware that feedback is usually coming from dissatisfied users. So when one judges whether a drug is effective online you have to factor in the fact that people who have had difficulties tend to post. Happy campers don't. BTW, I have seen posts here stating all SSRIs are nearly identical. That is clearly not the case. Prozac worked beautifully for me Lexapro was a bust. Your mileage may vary.
My Doc and I both agree our next choices should be either Zoloft or Luvox. She suggests Zoloft I came up with Luvox. Luvox (generic) is rarely prescribed in the US. However, it is only FDA approved for OCD and sufferers seem to like it. On the other hand, I think the Pdoc prefers what she knows best. Zoloft. I'd love to know what y'all have to say. Luvox or Zoloft? You Luvox users will be few in number so please chime in. Thanks in advance.