Horrific weight gain with Lexapro

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New Member

Date Joined Feb 2007
Total Posts : 2
   Posted 2/2/2007 2:17 AM (GMT -6)   
I've been on the Lex for about 2 1/2 years... 60 lbs gained. It's so strange to go from being a very naturally skinny person to being large. Somedays I feel like I'm wearing a fat suit, and I just want to unzip it and step out... That's how unfamiliar I am with my body... I've tried the wholer gamut of SSRIs for my OCD/Panic and have had the same results...

So yes, I know all SSRI's do the same thing to me (major weight gain) ... but what I'm wondering is when we will start to see some novel treatments? Big Pharma just keeps giving us "me too" drugs... There's no innovation. I don't know how much longer I can deal with the weight issue... It's starting to effect my health... Sleep Apena, Gerd, and joint issues. I'm 28, and yet I feel so old... mad

Elite Member

Date Joined Jan 2005
Total Posts : 24909
   Posted 2/2/2007 4:43 AM (GMT -6)   
Hi there and Welcome
I am sure there will be those on this med that will be able to help you out much more than I am able as I do not take it but wanted to say hello and tell you that you have found a great support system right here in HW
It wont take long to become aquainted with all and share info and find that support
Please do keep posting and again sorry I cannot hlp with this one but welcome
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Veteran Member

Date Joined Oct 2005
Total Posts : 2500
   Posted 2/2/2007 6:06 AM (GMT -6)   
Welcome to Healingwell...

Have you done anything different since going on the meds? Do you work out and eat right? Just saying the med may not be the only contributor...
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Veteran Member

Date Joined Jul 2006
Total Posts : 789
   Posted 2/2/2007 7:38 AM (GMT -6)   
Hello esokev
Welcome to HW were so happy you have joined us here. You will find great support here and make a lot of new friends going thru the same things you are so please post often so we know how you are doing.
I deffanently understand how you feel about the weight gain. I have always been naturely skinny barely reaching over 100 lbs at 9 months pregnant and delivery. When I was 46 I weighed 110 I am 48 now and I got up to 135 ( I know ladies thats not bad but on me it was). I started drinking Ensure every morning for breakfast so I could take my meds then have fruit or something healthy for lunch then eat supper around 5:00 pm and nothing after that. I have gotten back down to 115 and that's where I will stay. I also eat dry cereal if I feel I need to snack. Hope this helps you hun and yes I'm still on all of my meds for pain, anxiety and depression.

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Regular Member

Date Joined Jan 2007
Total Posts : 184
   Posted 2/2/2007 8:00 AM (GMT -6)   
Weight gain always stinks, but unfortunately, it's hard to know in advance which med is going to do it to you. All of the SSRIs can cause weight gain over time, with Paxil generally being the worst and Prozac being the best. Lexapro is too new to evaluate, but I've heard of plenty of people gaining on it.

Zoloft has been pretty good to me in the weight area. I haven't gained a lot, but I never completely lost the Paxil weight I put on.

Veteran Member

Date Joined Sep 2006
Total Posts : 657
   Posted 2/2/2007 8:00 AM (GMT -6)   

Have you talked to your doc about how unhappy you are? If you don't tell anyone it's broken they can't fix it (if only I took my own advise lol).

Also I have heard of people losing weight on Topamax - whether this would be suitable for you and your situation I could not say but it might be worth looking into.


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New Member

Date Joined Feb 2007
Total Posts : 2
   Posted 2/2/2007 1:29 PM (GMT -6)   
I did try Topamax actually... I was on it for a year, and lost about 5 lbs... but the kidney stones were unbearable. I used to dance in theater productions and such (which I can no longer do on a professional level, because of what has happened to my body) and my psychiatrists response was "well can you dance at home to get some more exercise?" I was dumfounded...

I eat healthy... No white sugars or flours, lots of fresh vegetables and lean proteins, whole grains... I don't mean to sound like a whiner, but sometimes it helps just to vent...

Veteran Member

Date Joined Nov 2006
Total Posts : 1052
   Posted 2/3/2007 7:51 PM (GMT -6)   

I'm on Lexapro 20mgs and have not gained any weight on it but I do have to watch what I eat as I have Diabetes but carbs and sugers are a big no no for me and even some fruits can bring it up but that's just me but since I been on this diet I have lost over 40pds in the past 3 years and now I'm at 175 now and back to the weight I was in high school, not to bad for a 45 year old man lol

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Veteran Member

Date Joined Sep 2006
Total Posts : 934
   Posted 2/3/2007 9:19 PM (GMT -6)   
Could you try a different anti depressant that isn't an SSRI?

Maybe I think it's called.... Wellbutrin or something like that? There are other anti depressants out there that are not SSRIs.

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RX: Lorazepam (1 MG a day), Lexapro (20 MG a day), Tylonel for the TMJ and Migraines
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New Member

Date Joined Feb 2007
Total Posts : 7
   Posted 2/3/2007 11:49 PM (GMT -6)   
Yes, my mom takes imiprimine (older class of anti-depressant)  luckily for her it has controlled her panic for 20 + years. It is not an SSRI and I don't think she's gained any weight over the years that could be attributed to her med. I take prozac, and have had no weight gain, however when I took paxil, i gained 20 lbs.  Good luck...Grizabella
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