After 13+ plus years at this, have lost much of my body hair. I once observed to my wife that she had more leg hair than me. You can imagine how well that went. Didn’t restore the bling to my crown...
So after seven months down the well trodden path of Degarelix /Lupron/XTANDI my MO has instituted a Pause. Treatment took PSA down from 18.6 to .19. Evaluate in three months. Last round of ADT lead...
OK Golfer, You have already received some very thoughtful replies from members on this Board. I think the best thought I can add is that I was diagnosed with a Gleason 8 in 2009 and I am still here....
Trailguy, Very difficult and troubling SE. Glad that you are feeling better and that PSA remains well contained… Bill...
Msttam, Great news as I am a relatively new X man, combined with 3 mo Lupron. Have had very good results. When I met with my MO in April to discuss systemic treatment, I asked his views about Zytiga...
Thank you Mattam. Clarifies. At 79 I rather am intrigued by a T level of 3,000. Not even in my horniest teenage days… Bill...
Onthefence, I have been at this for 13+ years, am on my third round of ADT, but my life has certainly been worthwhile — full, active, with my beautiful wife by my side. There is a famous essay on Old...
After your urologist assesses your PSA, and certainly does another DRE, may recommend a biopsy. Do not be put off by this. It is a few minutes of discomfort, a little blood in my case. Not a big...
I had a right hip replacement in the summer of ‘21 while on Lupron. No problems. Recovery was normal. I know normal for me because I had the same surgery on my left hip in ‘07, a few years before...
Great news Steve. Happy for you....
I don’t know anyone who made it into their 90s who was not miserable. Too much goes wrong. Dementia is the worst. I have a 94 year old friend in memory care. I had intended one recent day to have...
After 13+ years of treatment, I will take any nuts I can get....
Dave ‘68 and IsItSerious, I have been a patient at MSK for11+ years. In meetings my MO has always emphasized weighing a balance between the deleterious effects of ADT and the risks presented by the...
81GuyGuy, I have always loved that passage from As You Like It. Talk of a show stopper. The Bard only reached 51, so he missed some of the last bits. Astounds me how many of my friends in their 70s...
The best comment I have ever read about enjoying old age comes from an essay by Cicero. He is asked by his imaginary interlocutor “Is it possible to enjoy life in old age.” Cicero replies by...
Prato, Another, very important aspect of the decisions doctors make, is that there is very little percentage for them to vary much outside the standard of care. Factors always lurking behind the...
I wouldn’t either. Congratulations!...
Hi Mark, My wife and I live in Albany. I suppose I have had near 100 appointments and treatments at MSK over the years, and used AMTRAK for every appointment, sometimes alone, sometimes with my wife....
Hi Mark, To echo other posts, I think you did the right thing going to a major cancer center such as MSK. I had surgery in upstate NY in ‘09, but it was clear by summer of ‘11 that surgery had...
Steve, Great news. Specifically as this is your second round of treatment with LU-177. Thank you for keeping us up to date, and for your dogged persistence in getting a second round. Look forward to...
The major threat is clear and upon us. We live in a tripartite nuclear super power world that is inherently unstable and unpredictable. China, the US and Russia are in a dance where none can “trust”...
I have two titanium hips. Many airport security guys in consequence act as though they were my proctologists. Some more aggressive than others. Well it is at least safe sex....
To Our Moderators: This is an incredibly valuable post as guide to navigating the Mystery Tour of American health care and insurance. Lots of great information here that many men will find...
I would add pickle ball to the list of exercise options, but every person I know who has tried that activity has gotten injured....
Here is another something that seems effective (for me) and involves little time. Over the winter I read a piece in the NY Times (no surprise given my HW alias) citing a study claiming that short...
Yes, the Holy Grail is finding ways to defeat resistance… Bill...
Great stuff Steve. Thanks for the timely updates and news about supply....
Mal, and I thought I was a Long Hauler at 12 years and counting. Great story. And it is encouraging for younger guys. At 79, I defer to your experience and wisdom…. Bill...
No pain. Rising PSA led to scan and finding the met....
Great news Bohemond. May your hiatus run long and deep. Mattam, when I met with my MO in mid April, he was very up about Lupron/XTANDI combo and mentioned an as yet unpublished study. Probably the...
Great meeting place guys. My wife and I will be on the Vineyard end of August… Bill...
At night for sure, less likely to wake up too much during the inevitable 3 am visit....
Thanks for keeping us informed. A number of us probably have Pluvicto in our futures. Best wishes… Bill...
Same here. I only started XTANDI in April, but am experiencing fatigue right out of the box. When I do grounds work, I literally find myself needing to sit down after an hour or so on my feet — this...
Steve, SIMPLY GREAT. Really happy for you. You may well be the first American to receive a second course. Best wishes…. Bill...
Steve, Thank you for the informative and useful update. Wishing you well… Bill...
Intriguing. A lot of guys here do experience bad hot flashes....
With roughly 250,000 new cases of PCa reported each year in the US alone, there already is an enormous set of biopsy data. Using AI to employ that biopsy set would be a logical first step. Brave New...
Steve, Thanks for starting this thread and keeping us informed. Wish you all success…. Bill...
Hi Mattam, Yeah my MO and yours appear to be on the same page. I have gulped hard a few times looking at PSA levels, but I think he made the right call. As one X man to another, have a good one…. Bill...
Good and useful thread. Thanks to all. Mattam, I joined the Xtandi crowd a few days ago. Given my numbers and age, I doubt iADT will ever be in the cards. Most recent PSA is 18.6. Best news of late...
Happy Anniversary. And many more! …Bill...
Trailguy, me too… Bill...
A single federal judge recently issued a ruling demanding removal of an abortion drug from the market. Part of the judge’s ruling was that the FDA had not taken sufficient account of the...
Steve —. My situation is similar. A Gallium/68 PSMA scan (most sensitive scan technology available) a few weeks ago turned up no new mets, as compared to a PSMA last July. Yet my PSA is going up. My...
Mattam, I believe so too....
A team at Duke University Medical School has announced that they have identified a protein that is present on the surface of castrate resistant PCa cells. These resistant cells are neuroendocrine and...
Could be, hopefully, just a worn out hip that needs replacement. Very common surgery these days. I have had two hips replaced, which is, I believe, the maximum. “Leftie” was done in 2007, and still...
Jack, an ADT break is great for restoring energy, bone health, and a better sense of well being. There is always a trade off between the deleterious effects of treatment and those of the disease....
I was diagnosed with a Gleason 8 in 2009, and though it had been a long haul, I am still here. Multiple treatment options in the immediate and longer term. If you have access to a good medical...