I was trying to find out what the mechanisms are behind urgency, frequency etc are and one paper I was just reading may have some relevance here. Apparently in active colitis transit time in the...
There is evidence that combining FMT with a low sulphur diet increases the effectiveness and durability. https://onlinelibrary.wiley.com/doi/pdf/10.1111/jgh.16037 Probiotics at studied doses with low...
Also found VSL#3 beneficial but the dose needed (3600 billion cfu's/day for adults from trials) is very expensive if, as in my case, GP's or GI's, refuse to prescribe. There is a coupon scheme from...
Hope it works well for you. If it was available to me I would certainly try it as it seems very safe and beneficial on a number of fronts. I also think the reason sometimes for less promising results...
The quote is from the full paper. HBOT looks like it could be useful for rescue of extreme cases in hospital but logistically it is unlikely to be available for 40 sessions to many with less severe...
From the two clinical trial reports. The quote is from the 2A trial - apologies, I should have provided the source....
It is unlikely to be a treatment option for the majority. It also seems to be a relatively short lived effect. In the first trial the outcomes were not very significantly different 12 months after...
The mechanism involved in the protective effect of smoking is thought to be activation of the AhR/il22 pathway by a dioxin type compound in smoke. There are safer ways to activate this including Qing...
Saccharomyces boulardii is one of the better probiotics for infectious diarrhea and there is also some evidence for therapeutic use in UC....
Quercetin acts on elements of inflammatory pathways (TNF/NF-kB/il17 etc) common to many issues including SpA and RA (and UC). It is not an answer in itself though, I was just pointing out that there...
Also regarding methotrexate, the flavonoid quercetin may be an alternative. It has shown efficacy in a clinical trial for rheumatoid arthritis....
It is possible entyvio/vedolizumab has actually induced or exacerbated the issue. https://ard.bmj.com/content/76/5/878.short "This is the first report on new onset or exacerbation of...
With prior consultation with his doctors you could consider psyllium seed husk. The recommended dose is ~8g three times a day with 0.6L water each time and it seems to be advisable to start with...
I don’t think anyone will be able to make a valid scientific argument that the pathology of UC is not inextricably linked with oxidative stress. Another possibility for antioxidant delivery to the...
I was reading a bit about hydrogen sulphide and possible methods to control sulphate reducing bacteria today and came across a reference to the use of sweet tea vine (Gymnostemma pentaphyllum). Might...
The reaction to pickles may have been due to the presence of sulphites. I think sulphate reducing bacteria can use sulphites and they seem to be part of the issue in UC or at least some iterations of...
I have ordered an oral (delta only) Tocotrienol made by the AC Grace company. Nutricology and Allergy Research also have similar and there are probably others. I use a hyaluronic acid suppository...
Vitamin E mentioned in the discussion was not something I had used unless it is naturally present in one of the interventions. I did a bit of reading to see what would be the best supplement and it...
All the supplements mentioned are available in Europe. Getting diet right first is probably more important and dosage then needs to be worked out in mg/kg based on available science. Many good...
This thread has been very useful to me and I too would like to thank VanJordan for the insights. The key is trying to understand mechanisms to achieve a stable remission/possible cure. It is only by...